Bao-Cun Zhang
Overview
Explore the profile of Bao-Cun Zhang including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
598
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0
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Recent Articles
1.
Dai Y, Idorn M, Serrero M, Pan X, Thomsen E, Narita R, et al.
Nature
. 2024 Jul;
632(8024):383-389.
PMID: 39048823
The brain is highly sensitive to damage caused by infection and inflammation. Herpes simplex virus 1 (HSV-1) is a neurotropic virus and the cause of herpes simplex encephalitis. It is...
2.
Zhang B, Laursen M, Hu L, Hazrati H, Narita R, Jensen L, et al.
Nat Commun
. 2024 Mar;
15(1):2760.
PMID: 38553448
The cGAS-STING pathway plays a crucial role in anti-tumoral responses by activating inflammation and reprogramming the tumour microenvironment. Upon activation, STING traffics from the endoplasmic reticulum (ER) to Golgi, allowing...
3.
van der Horst D, Kurmasheva N, Marqvorsen M, Assil S, Rahimic A, Kollmann C, et al.
Commun Biol
. 2024 Mar;
7(1):283.
PMID: 38454028
DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I...
4.
Prabakaran T, Troldborg A, Kumpunya S, Alee I, Marinkovic E, Windross S, et al.
EBioMedicine
. 2021 Apr;
66:103314.
PMID: 33813142
Background: Nucleic acids are potent stimulators of type I interferon (IFN-I) and antiviral defense, but may also promote pathological inflammation. A range of diseases are characterized by elevated IFN-I, including...
5.
Zhang B, Nandakumar R, Reinert L, Huang J, Laustsen A, Gao Z, et al.
Nat Immunol
. 2020 Sep;
21(11):1468-1469.
PMID: 32929276
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Zhang B, Nandakumar R, Reinert L, Huang J, Laustsen A, Gao Z, et al.
Nat Immunol
. 2020 Jul;
21(8):868-879.
PMID: 32690950
STING is essential for control of infections and for tumor immunosurveillance, but it can also drive pathological inflammation. STING resides on the endoplasmic reticulum (ER) and traffics following stimulation to...
7.
Bodda C, Reinert L, Fruhwurth S, Richardo T, Sun C, Zhang B, et al.
J Exp Med
. 2020 May;
217(7).
PMID: 32383759
Herpes simplex virus (HSV) is the main cause of viral encephalitis in the Western world, and the type I interferon (IFN) system is important for antiviral control in the brain....
8.
Guan X, Zhang B, Sun L
Dev Comp Immunol
. 2019 Nov;
103:103531.
PMID: 31668931
MicroRNAs (miRNAs) are post-transcriptional regulators that play vital roles in diverse physiological processes including immunity. In this study, we investigated the regulatory mechanism and function of a novel Japanese flounder...
9.
Sun C, Luecke S, Bodda C, Jonsson K, Cai Y, Zhang B, et al.
J Interferon Cytokine Res
. 2019 Mar;
39(4):191-204.
PMID: 30855198
Incoming viruses challenge the cell with diverse foreign molecules, which need to be sensed quickly to initiate immune responses and to remove the viral components. In this study, we investigate...
10.
Nandakumar R, Tschismarov R, Meissner F, Prabakaran T, Krissanaprasit A, Farahani E, et al.
Nat Microbiol
. 2019 Feb;
4(4):701-713.
PMID: 30804548
The innate immune system is crucial for eventual control of infections, but may also contribute to pathology. Listeria monocytogenes is an intracellular Gram-positive bacteria and a major cause of food-borne...