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Rami Aqeilan

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Citations 565
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Recent Articles
1.
Amar-Schwartz A, Ben Hur V, Jbara A, Cohen Y, Barnabas G, Arbib E, et al.
Elife . 2022 Oct; 11. PMID: 36189922
The mTORC1 substrate, S6 Kinase 1 (S6K1), is involved in the regulation of cell growth, ribosome biogenesis, glucose homeostasis, and adipogenesis. Accumulating evidence has suggested a role for mTORC1 signaling...
2.
Peretz L, Besser E, Hajbi R, Casden N, Ziv D, Kronenberg N, et al.
Sci Rep . 2018 Jan; 8(1):93. PMID: 29311693
Inhibition of genes is a powerful approach to study their function. While RNA interference is a widely used method to achieve this goal, mounting evidence indicates that such an approach...
3.
Sundvall M, Veikkolainen V, Kurppa K, Salah Z, Tvorogov D, van Zoelen E, et al.
Mol Biol Cell . 2010 Oct; 21(23):4275-86. PMID: 20943952
The significance of ErbB4 in tumor biology is poorly understood. The ERBB4 gene is alternatively spliced producing juxtamembrane (JM-a and JM-b) and cytoplasmic (CYT-1 and CYT-2) isoforms. Here, signaling via...
4.
Volinia S, Galasso M, Costinean S, Tagliavini L, Gamberoni G, Drusco A, et al.
Genome Res . 2010 May; 20(5):589-99. PMID: 20439436
We studied miRNA profiles in 4419 human samples (3312 neoplastic, 1107 nonmalignant), corresponding to 50 normal tissues and 51 cancer types. The complexity of our database enabled us to perform...
5.
Salah Z, Aqeilan R, Huebner K
Future Oncol . 2010 Feb; 6(2):249-59. PMID: 20146584
The WWOX gene, an archetypal fragile gene, encompasses a chromosomal fragile site at 16q23.2, and encodes the approximately 46-kDa Wwox protein, with WW domains that interact with a growing list...
6.
Garzon R, Pichiorri F, Palumbo T, Iuliano R, Cimmino A, Aqeilan R, et al.
Proc Natl Acad Sci U S A . 2006 Mar; 103(13):5078-83. PMID: 16549775
microRNAs are a highly conserved class of noncoding RNAs with important regulatory functions in proliferation, apoptosis, development, and differentiation. To discover novel regulatory pathways during megakaryocytic differentiation, we performed microRNA...
7.
Zanesi N, Aqeilan R, Drusco A, Kaou M, Sevignani C, Costinean S, et al.
Cancer Res . 2006 Jan; 66(2):915-20. PMID: 16424025
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the world. The TCL1 gene, responsible for prolymphocytic T cell leukemia, is also overexpressed in human B cell malignancies and...
8.
Segel M, Aqeilan R, Zilka K, Lorberboum-Galski H, Wallach-Dayan S, Conner M, et al.
Int J Exp Pathol . 2005 Sep; 86(5):279-88. PMID: 16191100
The role of lymphocytes in the pathogenesis of lung fibrosis is not clear, but the weight of the evidence supports a pro-fibrotic effect for lymphocytes. The high-affinity interleukin-2 receptor (haIL-2R)...
9.
Sarti M, Sevignani C, Calin G, Aqeilan R, Shimizu M, Pentimalli F, et al.
Clin Cancer Res . 2005 Feb; 11(2 Pt 1):806-13. PMID: 15701871
Purpose: The human TESTIN (TES) gene is a putative tumor suppressor gene in the fragile chromosomal region FRA7G at 7q31.1/2 that was reported to be altered in leukemia and lymphoma...
10.
Pekarsky Y, Zanesi N, Aqeilan R, Croce C
Hematol Oncol Clin North Am . 2004 Aug; 18(4):863-79, ix. PMID: 15325703
Mature leukemias and lymphomas are a heterogeneous group of lymphoproliferative neoplasias characterized by the accumulation of mature lymphocytes in lymph nodes, other lymphoid tissues, and peripheral blood. In this article...