Tcl1 As a Model for Lymphomagenesis

Overview

Journal Hematol Oncol Clin North Am

Specialties Hematology
Oncology

Date 2004 Aug 25

PMID 15325703

Citations 3

Authors

Yuri Pekarsky

Nicola Zanesi

Rami Aqeilan

Carlo M Croce

Affiliations

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Abstract

Mature leukemias and lymphomas are a heterogeneous group of lymphoproliferative neoplasias characterized by the accumulation of mature lymphocytes in lymph nodes, other lymphoid tissues, and peripheral blood. In this article we discuss molecular mechanisms leading to the pathogenesis of two major types of mature leukemias and lymphomas: mature T-cell leukemia and chronic lymphocytic leukemia.

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