Ramanuj DasGupta
Overview
Explore the profile of Ramanuj DasGupta including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
74
Citations
2726
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen Y, Davidson N, Kei Wan Y, Yao F, Su Y, Gamaarachchi H, et al.
Nat Methods
. 2025 Mar;
PMID: 40082608
The human genome contains instructions to transcribe more than 200,000 RNAs. However, many RNA transcripts are generated from the same gene, resulting in alternative isoforms that are highly similar and...
2.
Neo S, Shuen T, Khare S, Chong J, Lau M, Shirgaonkar N, et al.
JCI Insight
. 2025 Feb;
PMID: 39998891
The functional plasticity of tumor-infiltrating B (TIL-B) cells spans from anti-tumor responses to non-canonical immune suppression. Yet, how tumor microenvironment (TME) influences TIL-B development is still underappreciated. Our current study...
3.
Dehkordi S, Wong I, Ni J, Luebeck J, Zhu K, Prasad G, et al.
Nat Commun
. 2025 Feb;
16(1):1497.
PMID: 39929823
Oncogene amplification is a key driver of cancer pathogenesis. Both breakage fusion bridge (BFB) cycles and extrachromosomal DNA (ecDNA) can lead to high oncogene copy numbers, but the impact of...
4.
Chong W, Low J, Tay J, Le T, Goh G, Sooi K, et al.
Lancet Oncol
. 2025 Jan;
26(2):175-186.
PMID: 39826567
Background: Vascular endothelial growth factor (VEGF) is overexpressed in nasopharyngeal carcinoma and suppresses the anti-tumour immune response. Previous studies have shown that adding anti-VEGF treatment to PD-1 inhibition treatment strategies...
5.
Womersley H, Muliaditan D, DasGupta R, Cheow L
Genome Res
. 2024 Dec;
35(1):162-177.
PMID: 39622638
Interrogating regulatory epigenetic alterations during tumor progression at the resolution of single cells has remained an understudied area of research. Here we developed a highly sensitive single-nucleus CUT&RUN (snCUT&RUN) assay...
6.
Singh V, Mondal A, Adhikary S, Mondal P, Shirgaonkar N, DasGupta R, et al.
ACS Infect Dis
. 2024 Jun;
10(11):3775-3796.
PMID: 38938101
A newly discovered E3 ubiquitin ligase, UBR7, plays a crucial role in histone H2BK120 monoubiquitination. Here, we report a novel function of UBR7 in promoting hepatitis B virus (HBV) pathogenesis,...
7.
Gan W, Ren X, Ng V, Ng L, Song Y, Tano V, et al.
Cell Rep
. 2024 Jun;
43(7):114400.
PMID: 38935501
ADAR1-mediated RNA editing establishes immune tolerance to endogenous double-stranded RNA (dsRNA) by preventing its sensing, primarily by MDA5. Although deleting Ifih1 (encoding MDA5) rescues embryonic lethality in ADAR1-deficient mice, they...
8.
Shanmugam R, Majee P, Shi W, Ozturk M, Vaiyapuri T, Idzham K, et al.
Cancer Discov
. 2024 Jun;
14(10):1940-1963.
PMID: 38885349
Over-consumption of iron-rich red meat and hereditary or genetic iron overload are associated with an increased risk of colorectal carcinogenesis, yet the mechanistic basis of how metal-mediated signaling leads to...
9.
Scolaro T, Manco M, Pecqueux M, Amorim R, Trotta R, Van Acker H, et al.
Nat Cancer
. 2024 Jun;
5(8):1206-1226.
PMID: 38844817
Many individuals with cancer are resistant to immunotherapies. Here, we identify the gene encoding the pyrimidine salvage pathway enzyme cytidine deaminase (CDA) among the top upregulated metabolic genes in several...
10.
Tostado C, Da Ong L, Heng J, Miccolis C, Chia S, Seow J, et al.
Bioeng Transl Med
. 2024 Mar;
9(2):e10628.
PMID: 38435825
We present a novel framework combining single-cell phenotypic data with single-cell transcriptomic analysis to identify factors underpinning heterogeneity in antitumor immune response. We developed a pairwise, tumor-immune discretized interaction assay...