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Ramanjit Gill

Explore the profile of Ramanjit Gill including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 167
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Recent Articles
1.
Gill R, Kemp J, Sabin C, Pepys M
J Cereb Blood Flow Metab . 2004 Nov; 24(11):1214-8. PMID: 15545914
Human C-reactive protein (CRP), the classic acute phase plasma protein, increases in concentration after myocardial infarction and stroke. Human CRP binds to ligands exposed in damaged tissue and can then...
2.
Alanine A, Bourson A, Buttelmann B, Gill R, Heitz M, Mutel V, et al.
Bioorg Med Chem Lett . 2003 Sep; 13(19):3155-9. PMID: 12951084
Screening of the Roche compound depository led to the identification of (1-benzyloxy-4,5-dihydro-1H-imidazol-2-yl)-butyl amine 4, a structurally novel NR1/2B subtype selective NMDA receptor antagonist. The structure-activity relationships developed in this series...
3.
Buttelmann B, Alanine A, Bourson A, Gill R, Heitz M, Mutel V, et al.
Bioorg Med Chem Lett . 2003 May; 13(10):1759-62. PMID: 12729659
A series of 4-(3,4-dihydro-1H-isoquinolin-2yl)-pyridines and analogous quinolines was prepared and evaluated as NR1/2B subtype selective NMDA receptor antagonists. 2-Hydroxyalkylamino substitution combines high affinity with selectivity (vs alpha1 and M1 receptors)...
4.
Roth A, Gill R, Certa U
Mol Cell Neurosci . 2003 Apr; 22(3):353-64. PMID: 12691737
We have used the middle cerebral artery occlusion model in the rat in combination with microarray transcript imaging to study changes in gene activity after ischemic stroke. We analyze transcriptional...
5.
Buttelmann B, Alanine A, Bourson A, Gill R, Heitz M, Mutel V, et al.
Bioorg Med Chem Lett . 2003 Mar; 13(5):829-32. PMID: 12617901
Recently, we disclosed 4-aminoquinolines as structurally novel NR1/2B subtype selective NMDA receptor antagonists. We would now like to report our findings on structurally related pyridine analogues. The SAR developed in...
6.
Gill R, Soriano M, Blomgren K, Hagberg H, Wybrecht R, Miss M, et al.
J Cereb Blood Flow Metab . 2002 Mar; 22(4):420-30. PMID: 11919513
These studies have addressed the role of caspase-3 activation in neuronal death after cerebral ischemia in different animal models. The authors were unable to show activation of procaspase-3 measured as...
7.
Gretarsdottir S, Sveinbjornsdottir S, Jonsson H, Jakobsson F, Einarsdottir E, Agnarsson U, et al.
Am J Hum Genet . 2002 Feb; 70(3):593-603. PMID: 11833004
Stroke is one of the most complex diseases, with several subtypes, as well as secondary risk factors, such as hypertension, hyperlipidemia, and diabetes, which, in turn, have genetic and environmental...