Ralph Haygood
Overview
Explore the profile of Ralph Haygood including associated specialties, affiliations and a list of published articles.
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21
Citations
891
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Recent Articles
11.
Tung J, Fedrigo O, Haygood R, Mukherjee S, Wray G
Mol Biol Evol
. 2009 Jun;
26(9):2047-59.
PMID: 19506001
Variation in gene expression is an important contributor to phenotypic diversity within and between species. Although this variation often has a genetic component, identification of the genetic variants driving this...
12.
Haygood R, Turelli M
Evolution
. 2009 Jan;
63(2):432-47.
PMID: 19154372
Many insects, other arthropods, and nematodes harbor maternally inherited bacteria inducing "cytoplasmic incompatibility" (CI), reduced egg hatch when infected males mate with uninfected females. Although CI drives the spread of...
13.
Walters J, Binkley E, Haygood R, Romano L
Dev Biol
. 2008 Feb;
315(2):567-78.
PMID: 18262514
An evolutionary analysis of transcriptional regulation is essential to understanding the molecular basis of phenotypic diversity. The sea urchin is an ideal system in which to explore the functional consequence...
14.
Babbitt C, Haygood R, Wray G
Cell
. 2007 Oct;
131(2):225-7.
PMID: 17956721
Gene duplication and divergence has long been considered an important route to adaptation and phenotypic evolution. Reporting in Nature, Hittinger and Carroll (2007) provide the first clear example of adaptations...
15.
Spitzer B, Haygood R
Am Nat
. 2007 Sep;
170(4):567-72.
PMID: 17891735
The frozen niche variation hypothesis suggests that sexuals can coexist with closely related, ecologically similar asexuals because sexuals and narrowly adapted asexual clones use different resources. However, because a collection...
16.
Haygood R, Fedrigo O, Hanson B, Yokoyama K, Wray G
Nat Genet
. 2007 Aug;
39(9):1140-4.
PMID: 17694055
Surveys of protein-coding sequences for evidence of positive selection in humans or chimpanzees have flagged only a few genes known to function in neural or nutritional processes, despite pronounced differences...
17.
Sodergren E, Weinstock G, Davidson E, Cameron R, Gibbs R, Angerer R, et al.
Science
. 2006 Nov;
314(5801):941-52.
PMID: 17095691
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and...
18.
Haygood R
Mol Biol Evol
. 2006 Feb;
23(5):957-63.
PMID: 16469852
Two recent theoretical studies of adaptation suggest that more complex organisms tend to adapt more slowly. Specifically, in Fisher's "geometric" model of a finite population where multiple traits are under...
19.
Haygood R
Evolution
. 2004 Sep;
58(7):1414-23.
PMID: 15341145
Sexual conflict, where male and female reproductive interests differ, is probably widespread and often mediated by male or sperm proteins and female or egg proteins that bind to each other...
20.
Haygood R, Ives A, Andow D
Proc Biol Sci
. 2003 Oct;
270(1527):1879-86.
PMID: 14561300
Concern about gene flow from crops to wild relatives has become widespread with the increasing cultivation of transgenic crops. Possible consequences of such gene flow include genetic assimilation, wherein crop...