Ralf Labugger
Overview
Explore the profile of Ralf Labugger including associated specialties, affiliations and a list of published articles.
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10
Citations
84
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Recent Articles
1.
van der Loo B, Bachschmid M, Skepper J, Labugger R, Schildknecht S, Hahn R, et al.
Biochem Biophys Res Commun
. 2006 Apr;
344(3):972-80.
PMID: 16631605
Vascular aging is characterized by the presence of chronic oxidative stress. Although cytosolic Sod 1 has a key role in the detoxification of superoxide ((*)O(2)(-)), little is known about its...
2.
van der Loo B, Bachschmid M, Labugger R, Schildknecht S, Kilo J, Hahn R, et al.
Biogerontology
. 2006 Feb;
6(5):325-34.
PMID: 16463109
We investigated the effects of aging and ischemia-reperfusion (I/R) injury on the expression and activity of nitric oxide (*NO) synthases and superoxide dismutase (SOD) isoforms. To this end we perfused...
3.
Simpson J, Labugger R, Collier C, Brison R, Iscoe S, Van Eyk J
Clin Chem
. 2005 Apr;
51(6):966-72.
PMID: 15833785
Background: Detection of skeletal muscle injury is hampered by a lack of commercially available assays for serum markers specific for skeletal muscle; serum concentrations of skeletal troponin I (sTnI) could...
4.
Bachschmid M, van der Loo B, Schuler K, Labugger R, Thurau S, Eto M, et al.
Arch Gerontol Geriatr
. 2003 Dec;
38(2):181-90.
PMID: 14698497
Aging is an independent risk factor for the development of cardiovascular disease. Vascular aging is mainly characterized by endothelial dysfunction, which, in turn, is primarily attributable to increased superoxide (O(2)(*)(-))...
5.
van der Loo B, Labugger R, Aebischer C, Bachschmid M, Spitzer V, Kilo J, et al.
J Cardiovasc Pharmacol
. 2003 Dec;
43(1):26-30.
PMID: 14668564
Ageing is an independent risk factor for the development of cardiovascular disease. The ageing process is known to be associated with increased oxidative stress and an increased risk for cardiovascular...
6.
Labugger R, Simpson J, Quick M, Brown H, Collier C, Neverova I, et al.
Clin Chem
. 2003 May;
49(6 Pt 1):873-9.
PMID: 12765982
Background: Cardiac troponins are modified during ischemic injury and are found as a heterogeneous mixture in blood of patients with cardiovascular diseases. We present a strategy to isolate cardiac troponins...
7.
Atar D, Madsen L, Labugger R, VanEyk J
Ugeskr Laeger
. 2003 Jan;
165(2):116-20.
PMID: 12553091
Introduction: Cardiac troponin I and T (cTnI and cTnT) are specific biochemical serum markers for acute myocardial infarction (AMI). However, cTnI diagnostic assays are plagued by difficulties, resulting in >...
8.
Labugger R, McDonough J, Neverova I, Van Eyk J
Proteomics
. 2002 Jul;
2(6):673-8.
PMID: 12112847
Proteomics strongly relies on the separation of complex protein mixtures, with two-dimensional electrophoresis (2-DE) being a commonly used technique. However efficient separation requires adequate solubilization of the original sample which...
9.
Simpson J, Labugger R, Hesketh G, DArsigny C, ODonnell D, Matsumoto N, et al.
Clin Chem
. 2002 Jun;
48(7):1112-4.
PMID: 12089186
No abstract available.
10.
van der Loo B, Labugger R, Aebischer C, Skepper J, Bachschmid M, Spitzer V, et al.
Circulation
. 2002 Apr;
105(14):1635-8.
PMID: 11940539
Background: Aging is an independent risk factor for the development of cardiovascular disease. Therefore, therapies to delay vascular aging may have enormous medical consequences. In this context, vitamin E is...