Rajkumar Dorajoo
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Explore the profile of Rajkumar Dorajoo including associated specialties, affiliations and a list of published articles.
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85
Citations
5561
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Recent Articles
1.
Chang X, Shih C, Chen J, Lee A, Tan P, Wang L, et al.
medRxiv
. 2025 Feb;
PMID: 39990559
Background: Existing polygenic scores (PGS) are derived primarily from studies performed in European populations. It is still unclear how these perform in improving risk predictions in East-Asians. Methods: We generated...
2.
Tay J, Wang W, Guan L, Dorajoo R, Khor C, Feng L, et al.
J Gerontol A Biol Sci Med Sci
. 2025 Jan;
PMID: 39869450
Deoxyribonucleic acid (DNA) methylation (DNAm) clocks estimate biological age according to DNA methylation. This study investigated the associations between measures of physical function and physical performance and ten DNAm clocks...
3.
Cui Q, Tan W, Song B, Peng R, Wang L, Dorajoo R, et al.
Leukemia
. 2024 Dec;
39(3):694-702.
PMID: 39707004
Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy and the most common form of non-Hodgkin lymphoma (NHL) that occurs worldwide. To discover risk factors and pathogenesis of DLBCL, we...
4.
Chen Y, Torta F, Koh H, Benke P, Gurung R, Liu J, et al.
Diabetologia
. 2024 Dec;
68(3):557-575.
PMID: 39621102
Aims/hypothesis: This study aims to explore the association between plasma metabolites and chronic kidney disease progression in individuals with type 2 diabetes. Methods: We performed a comprehensive metabolomic analysis in...
5.
Naaz A, Zhang Y, Faidzinn N, Yogasundaram S, Dorajoo R, Alfatah M
Cells
. 2024 Sep;
13(17.
PMID: 39273040
Aging is an inevitable biological process that contributes to the onset of age-related diseases, often as a result of mitochondrial dysfunction. Understanding the mechanisms behind aging is crucial for developing...
6.
The Causal Effect of Adult Height on Late-Life Handgrip Strength: The Singapore Chinese Health Study
Chang X, Chua K, Shih C, Chen J, Lee A, Tan P, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Aug;
79(11).
PMID: 39193984
Background: Adult height has been associated with handgrip strength, which is a surrogate marker of physical frailty. However, it is uncertain if this association is causative or due to confounding...
7.
Ho P, Khng A, Tan B, Khor C, Tan E, Lim G, et al.
Cancers (Basel)
. 2024 Jun;
16(11).
PMID: 38893190
Purpose: To assess the association of a polygenic risk score (PRS) for functional genetic variants with the risk of developing breast cancer. Methods: Summary data-based Mendelian randomization (SMR) and heterogeneity...
8.
Zhang J, Ye Y, Dorajoo R, Khor C, Chang X, Yu H, et al.
J Nutr
. 2023 Nov;
154(1):252-260.
PMID: 38035998
Background: It remains unclear if adherence to the planetary healthy diet (PHD), designed to improve human and environmental health, is associated with better cognitive function in aging, and if this...
9.
de las Fuentes L, Schwander K, Brown M, Bentley A, Winkler T, Sung Y, et al.
Front Genet
. 2023 Nov;
14:1235337.
PMID: 38028628
Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density...
10.
Ong S, Dehghan R, Dorajoo R, Liu J, Sng A, Lee Y, et al.
J Clin Endocrinol Metab
. 2023 Oct;
109(3):e1249-e1259.
PMID: 37820740
Context: Genetic variants in melanocortin 3 receptor (MC3R) and melanocortin 4 receptor (MC4R) genes are strongly associated with childhood obesity. Objective: This study aims to identify and functionally characterize MC3R...