Rajesh Ramachandran
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Explore the profile of Rajesh Ramachandran including associated specialties, affiliations and a list of published articles.
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77
Citations
2817
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Recent Articles
1.
Srivastava P, Bhasin S, Shankaran S, Roger C, Ramachandran R, Minocha S
Biol Methods Protoc
. 2024 Oct;
9(1):bpae073.
PMID: 39464854
Traumatic brain injury (TBI) can be caused by a sudden blow or jolt to the head, causing irreversible brain damage leading to cellular and functional loss. Mammals cannot repair such...
2.
Sharma P, Ramachandran R
Oxf Open Neurosci
. 2024 Apr;
1:kvac012.
PMID: 38596712
Unlike mammals, vertebrates such as fishes and frogs exhibit remarkable tissue regeneration including the central nervous system. Retina being part of the central nervous system has attracted the interest of...
3.
Rochon K, Bauer B, Roethler N, Buckley Y, Su C, Huang W, et al.
Nat Commun
. 2024 Feb;
15(1):1328.
PMID: 38351080
Mitochondrial fission is a critical cellular event to maintain organelle function. This multistep process is initiated by the enhanced recruitment and oligomerization of dynamin-related protein 1 (Drp1) at the surface...
4.
Perez-Jover I, Rochon K, Hu D, Mahajan M, Madan Mohan P, Santos-Perez I, et al.
Nat Commun
. 2024 Jan;
15(1):52.
PMID: 38168038
The mechanochemical GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial and peroxisomal fission, but the regulatory mechanisms remain ambiguous. Here we find that a conserved, intrinsically disordered, six-residue Short Linear Motif...
5.
Sathyan K, Premraj A, Chaudhary M, Ramachandran R, Puthiyedathu S
Dev Comp Immunol
. 2023 Sep;
149:105062.
PMID: 37726038
The Stimulator of Interferon Genes (STING, also known as MITA/ERYS/MPYS) is an adaptor molecule that plays a crucial role in the RLR pathway and responds to DNA and RNA viruses....
6.
Perez-Jover I, Rochon K, Hu D, Madan Mohan P, Santos-Perez I, Ormaetxea Gisasola J, et al.
Res Sq
. 2023 Jul;
PMID: 37503116
The mechanochemical GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial fission, but the regulatory mechanisms remain ambiguous. Here we found that a conserved, intrinsically disordered, six-residue hort near otif at the...
7.
Bauer B, Rochon K, Liu J, Ramachandran R, Mears J
Hum Mol Genet
. 2023 Feb;
32(12):1975-1987.
PMID: 36795043
Patient mutations have been identified throughout dynamin-related protein 1 (Drp1), the key protein mediator of mitochondrial fission. These changes generally impact young children and often result in severe neurological defects...
8.
Vaman R, Valamparampil M, Varghese B, Mathews E, Kunhiraman M, Ramachandran R
Natl Med J India
. 2022 Dec;
35(3):138-141.
PMID: 36461872
Background Symptoms of Covid-19 are known to be non-specific ranging from asymptomatic cases to severe illness affecting multiple organ systems. The duration of viral RNA positivity and transmission varies in...
9.
Mears J, Ramachandran R
Curr Opin Physiol
. 2022 Nov;
29.
PMID: 36406887
Dynamin-related protein 1 (Drp1), the master regulator of mitochondrial division (MD), interacts with the cytoskeletal elements, namely filamentous actin (F-actin), microtubules (MT), and septins that coincidentally converge at MD sites....
10.
Gupta S, Sharma P, Chaudhary M, Premraj S, Kaur S, Vijayan V, et al.
Glia
. 2022 Sep;
71(2):259-283.
PMID: 36128720
Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after an acute injury. Retina regeneration in zebrafish involves the induction of Müller glia-derived progenitor cells (MGPCs) exhibiting stem...