Rajesh Bhardwaj
Overview
Explore the profile of Rajesh Bhardwaj including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
284
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Recent Articles
1.
Tscherrig D, Bhardwaj R, Biner D, Dernic J, Ross-Kaschitza D, Peinelt C, et al.
Cell Calcium
. 2023 Nov;
117:102834.
PMID: 38006628
Many physiological functions, such as cell differentiation, proliferation, muscle contraction, neurotransmission and fertilisation, are regulated by changes of Ca levels. The major Ca store in cells is the endoplasmic reticulum...
2.
Kumar M, Michael S, Alvarado-Valverde J, Zeke A, Lazar T, Glavina J, et al.
Nucleic Acids Res
. 2023 Nov;
52(D1):D442-D455.
PMID: 37962385
Short Linear Motifs (SLiMs) are the smallest structural and functional components of modular eukaryotic proteins. They are also the most abundant, especially when considering post-translational modifications. As well as being...
3.
Sanchez-Collado J, Nieto-Felipe J, Jardin I, Bhardwaj R, Berna-Erro A, Salido G, et al.
Cancers (Basel)
. 2023 Jan;
15(1).
PMID: 36612199
N-linked glycosylation is a post-translational modification that affects protein function, structure, and interaction with other proteins. The store-operated Ca entry (SOCE) core proteins, Orai1 and STIM1, exhibit N-glycosylation consensus motifs....
4.
Mishra R, Kumar V, Trung L, Choi G, Ryu J, Bhardwaj R, et al.
Luminescence
. 2022 Nov;
38(7):1087-1101.
PMID: 36398418
Air pollution is a severe concern globally as it disturbs the health conditions of living beings and the environment because of the discharge of acetone molecules. Metal oxide semiconductor (MOS)...
5.
Augustynek B, Gyimesi G, Dernic J, Sallinger M, Albano G, Klesse G, et al.
Cell Calcium
. 2022 Jul;
105:102616.
PMID: 35792401
In humans, there are three paralogs of the Orai Ca channel that form the core of the store-operated calcium entry (SOCE) machinery. While the STIM-mediated gating mechanism of Orai channels...
6.
Verouti S, Pujol-Gimenez J, Bermudez-Lekerika P, Scherler L, Bhardwaj R, Thomas A, et al.
Front Physiol
. 2022 Jul;
13:912277.
PMID: 35784893
The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the single-nucleotide polymorphism (SNP) variant A391T (rs13107325) is associated with...
7.
Kondampati K, Saini S, Sidhu P, Anand A, Kumar D, Beesam S, et al.
J Equine Vet Sci
. 2022 May;
115:104020.
PMID: 35605881
The pharmacokinetics of ampicillin-cloxacillin, given as single intravenously dose of 10 mg.kg (5 mg.kg of ampicillin plus 5 mg.kg of cloxacillin) was examined in clinically presented Indian thoroughbred horses (n ...
8.
Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Hoglinger C, et al.
Cancers (Basel)
. 2021 Dec;
13(24).
PMID: 34944977
The interplay of SK3, a Ca sensitive K ion channel, with Orai1, a Ca ion channel, has been reported to increase cytosolic Ca levels, thereby triggering proliferation of breast and...
9.
Pujol-Gimenez J, Poirier M, Buhlmann S, Schuppisser C, Bhardwaj R, Awale M, et al.
ChemMedChem
. 2021 Jul;
16(21):3306-3314.
PMID: 34309203
Solute carrier proteins (SLCs) are membrane proteins controlling fluxes across biological membranes and represent an emerging class of drug targets. Here we searched for inhibitors of divalent metal transporters in...
10.
Kandasamy P, Zlobec I, Nydegger D, Pujol-Gimenez J, Bhardwaj R, Shirasawa S, et al.
Mol Oncol
. 2021 May;
15(10):2782-2800.
PMID: 34003553
Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and...