Rajeev K Mehlotra
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Explore the profile of Rajeev K Mehlotra including associated specialties, affiliations and a list of published articles.
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Citations
573
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Recent Articles
11.
Willie N, Mehlotra R, Howes R, Rakotomanga T, Ramboarina S, Ratsimbasoa A, et al.
Am J Trop Med Hyg
. 2018 Mar;
98(6):1683-1691.
PMID: 29557337
histidine-rich protein 2 (PfHRP2) forms the basis of many current malaria rapid diagnostic tests (RDTs). However, the parasites lacking part or all of the gene do not express the PfHRP2...
12.
Mehlotra R, Blankenship D, Howes R, Rakotomanga T, Ramiranirina B, Ramboarina S, et al.
Malar J
. 2017 Nov;
16(1):442.
PMID: 29100506
Background: Plasmodium vivax is the most prevalent human malaria parasite and is likely to increase proportionally as malaria control efforts more rapidly impact the prevalence of Plasmodium falciparum. Despite the...
13.
Mehlotra R, Hall N, Willie B, Stein C, Weinberg A, Zimmerman P, et al.
PLoS One
. 2016 Oct;
11(10):e0164075.
PMID: 27727278
Polymorphisms in toll-like receptor (TLR) and β-defensin (DEFB) genes have been recognized as potential genetic factors that can influence susceptibility to and severity of periodontal diseases (PD). However, data regarding...
14.
Mehlotra R, Zimmerman P, Weinberg A
J Leukoc Biol
. 2016 Mar;
99(5):687-92.
PMID: 26957215
Both α- and β-defensins have anti-human immunodeficiency virus activity. These defensins achieve human immunodeficiency virus inhibition through a variety of mechanisms, including direct binding with virions, binding to and modulation...
15.
Mehlotra R, Hall N, Bruse S, John B, Zikursh M, Stein C, et al.
Infect Genet Evol
. 2015 Sep;
36:165-173.
PMID: 26397046
Polymorphisms in chemokine receptors, serving as HIV co-receptors, and their ligands are among the well-known host genetic factors associated with susceptibility to HIV infection and/or disease progression. Papua New Guinea...
16.
Cheruvu V, Igo Jr R, Jurevic R, Serre D, Zimmerman P, Rodriguez B, et al.
J Acquir Immune Defic Syndr
. 2014 Apr;
66(1):102-7.
PMID: 24714069
Introduction: In a North American, HIV-positive, highly active antiretroviral therapy (HAART)-treated, adherent cohort of self-identified white and black patients, we previously observed that chemokine (C-C motif) receptor 5 (CCR5) -2459G>A...
17.
Mehlotra R, Dazard J, John B, Zimmerman P, Weinberg A, Jurevic R
J AIDS Clin Res
. 2013 Apr;
3(10).
PMID: 23543857
Study Background: encoding β-defensin 2 and 3, respectively, inhibit CXCR4-tropic (X4) viruses in vitro. We determined whether Copy Number Variation (CNV) influences time-to-X4 and time-to-AIDS outcomes. Methods: We utilized samples...
18.
Li J, Menard V, Benish R, Jurevic R, Guillemette C, Stoneking M, et al.
Pharmacogenomics
. 2012 Apr;
13(5):555-70.
PMID: 22462748
Aim: Hepatic enzymes, CYP2B6 and UGT2B7 play a major role in the metabolism of the widely used antiretroviral drugs efavirenz, nevirapine and zidovudine. In the present study, we provide a...
19.
Mehlotra R, Cheruvu V, Zikursh M, Benish R, Lederman M, Salata R, et al.
J Infect Dis
. 2011 Jun;
204(2):291-8.
PMID: 21673041
Background: In patients receiving highly active antiretroviral therapy (HAART), antiretroviral drug-metabolizing enzyme and transporter gene polymorphisms, as well as chemokine receptor gene polymorphisms, may influence response to treatment. Methods: In...
20.
Grimberg B, Mehlotra R
Pharmaceuticals (Basel)
. 2011 Jun;
4(5):681-712.
PMID: 21625331
The number of available and effective antimalarial drugs is quickly dwindling. This is mainly because a number of drug resistance-associated mutations in malaria parasite genes, such as crt, mdr1, dhfr/dhps,...