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Benigno Rodriguez

Explore the profile of Benigno Rodriguez including associated specialties, affiliations and a list of published articles. Areas
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Articles 143
Citations 9059
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Recent Articles
1.
Chirenje Z, Laher F, Dintwe O, Muyoyeta M, deCamp A, He Z, et al.
J Infect Dis . 2023 Oct; 230(2):e405-e415. PMID: 37795976
Background: HVTN 120 is a phase 1/2a randomized double-blind placebo-controlled human immunodeficiency virus (HIV) vaccine trial that evaluated the safety and immunogenicity of ALVAC-HIV (vCP2438) and MF59- or AS01B-adjuvanted bivalent...
2.
Funderburg N, Shive C, Chen Z, Tatsuoka C, Bowman E, Longenecker C, et al.
Clin Infect Dis . 2023 Apr; 77(2):272-279. PMID: 37011013
Background: People with human immunodeficiency virus (PWH) are at increased risk for comorbidities, and plasma interleukin 6 (IL-6) levels are among the most robust predictors of these outcomes. Tocilizumab (TCZ)...
3.
Wilson G, Rodriguez B, Li S, Allen M, Frank I, Rudnicki E, et al.
Vaccine . 2023 Mar; 41(16):2696-2706. PMID: 36935288
Background: HIV subtypes B and C together account for around 60% of HIV-1 cases worldwide. We evaluated the safety and immunogenicity of a subtype B DNA vaccine prime followed by...
4.
Freeman M, Clagett B, Moisi D, Yeh E, Morris C, Ryu A, et al.
Front Immunol . 2022 Aug; 13:924718. PMID: 35967371
Inflammation associated with increased risk of comorbidities persists in people living with HIV (PWH) on combination antiretroviral therapy (ART). A recent placebo-controlled trial of low-dose methotrexate (MTX) in PWH found...
5.
Ferrari B, Cabral da Silva A, Liu K, Saidakova E, Korolevskaya L, Shmagel K, et al.
J Clin Invest . 2022 Mar; 132(9). PMID: 35316209
People living with HIV (PLWH) who are immune nonresponders (INRs) are at greater risk of comorbidity and mortality than are immune responders (IRs) who restore their CD4+ T cell count...
6.
Nganou-Makamdop K, Talla A, Sharma A, Darko S, Ransier A, Laboune F, et al.
Cell . 2021 Jul; 184(15):3899-3914.e16. PMID: 34237254
The impact of the microbiome on HIV disease is widely acknowledged although the mechanisms downstream of fluctuations in microbial composition remain speculative. We detected rapid, dynamic changes in translocated microbial...
7.
Shive C, Freeman M, Younes S, Kowal C, Canaday D, Rodriguez B, et al.
Front Immunol . 2021 Apr; 12:638010. PMID: 33868264
Immune non-responders (INR) are HIV+, ART-controlled (>2 yrs) people who fail to reconstitute their CD4 T cell numbers. Systemic inflammation and markers of T cell senescence and exhaustion are observed...
8.
Bajema K, Nance R, Delaney J, Eaton E, Davy-Mendez T, Karris M, et al.
AIDS . 2020 Oct; 34(14):2051-2059. PMID: 33055569
Objective: Historically, a high burden of resistance to antiretroviral therapy (ART) in heavily treatment-experienced (HTE) persons with HIV (PWH) resulted in limited treatment options (LTOs). We evaluated the prevalence, risk...
9.
Umbleja T, Brown T, Overton E, Ribaudo H, Schrack J, Fitch K, et al.
J Infect Dis . 2020 Jul; 222(Suppl 1):S52-S62. PMID: 32645163
Background: People with human immunodeficiency virus (PWH) are at risk for accelerated development of physical function impairment and frailty; both associated with increased risk of falls, hospitalizations, and death. Identifying...
10.
Morris S, Chen B, Mudd J, Panigrahi S, Shive C, Sieg S, et al.
JCI Insight . 2020 May; 5(11). PMID: 32369455
HIV infection is associated with an increase in the proportion of activated CD8+ memory T cells (Tmem) that express CX3CR1, but how these cells are generated and maintained in vivo...