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Rajashri Sridharan

Explore the profile of Rajashri Sridharan including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 52
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Recent Articles
1.
Connelly S, Sridharan R, Naider F, Dumont M
Biophys J . 2021 Oct; 120(22):5090-5106. PMID: 34627767
G-protein-coupled receptors (GPCRs) comprise a large superfamily of transmembrane receptors responsible for transducing responses to the binding of a wide variety of hormones, neurotransmitters, ions, and other small molecules. There...
2.
Krishna B, Wass A, Sridharan R, OConnor C
Front Cell Infect Microbiol . 2020 May; 10:186. PMID: 32411622
The ability to establish a latent infection with periodic reactivation events ensures herpesviruses, like human cytomegalovirus (HCMV), lifelong infection, and serial passage. The host-pathogen relationship throughout HCMV latency is complex,...
3.
Sridharan R, Connelly S, Naider F, Dumont M
J Biol Chem . 2016 Sep; 291(46):24261-24279. PMID: 27646004
We report here on the relationship between ligand binding and signaling responses in the yeast pheromone response pathway, a well characterized G protein-coupled receptor system. Responses to agonist (α-factor) by...
4.
Sridharan R, Zuber J, Connelly S, Mathew E, Dumont M
Biochim Biophys Acta . 2013 Sep; 1838(1 Pt A):15-33. PMID: 24055822
G protein coupled receptors are responsible for a wide variety of signaling responses in diverse cell types. Despite major advances in the determination of structures of this class of receptors,...