Benjamin A Krishna
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Explore the profile of Benjamin A Krishna including associated specialties, affiliations and a list of published articles.
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17
Citations
338
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Recent Articles
1.
Baruah V, Krishna B, Kelly M, Qi X, OConnor C
bioRxiv
. 2025 Feb;
PMID: 39990446
Reactivation of latent human cytomegalovirus (CMV) can lead to severe complications in individuals with dysregulated immune systems. While antiviral therapies for CMV are approved, these compounds are limited by their...
2.
Mukhopadhyay R, Lambisia A, Hoang J, Ravenhill B, Agoti C, Krishna B, et al.
J Med Virol
. 2025 Feb;
97(2):e70222.
PMID: 39921609
Human adenoviruses (HAdVs) cause diverse disease presentations as pathogens and are also used as viral vectors for vaccines and gene therapy products. Pre-existing adaptive immune responses to HAdV are known...
3.
Krishna B, Lim E, Metaxaki M, Jackson S, Mactavous L, Lyons P, et al.
Sci Adv
. 2024 Feb;
10(8):eadi9379.
PMID: 38381822
After acute infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a proportion of patients experience persistent symptoms beyond 12 weeks, termed Long Covid. Understanding the mechanisms that cause this debilitating...
4.
Ferreira I, Lee C, Foster W, Abdullahi A, Dratva L, Tuong Z, et al.
Cell Rep
. 2023 Aug;
42(8):112991.
PMID: 37590132
Suboptimal responses to a primary vaccination course have been reported in the elderly, but there is little information regarding the impact of age on responses to booster third doses. Here,...
5.
Wass A, Krishna B, Herring L, Gilbert T, Nukui M, Groves I, et al.
Sci Adv
. 2022 Oct;
8(43):eadd1168.
PMID: 36288299
Cytomegalovirus (CMV) reactivation from latency following immune dysregulation remains a serious risk for patients, often causing substantial morbidity and mortality. Here, we demonstrate the CMV-encoded G protein-coupled receptor, US28, in...
6.
Krishna B, Metaxaki M, Wills M, Sithole N
Clin Infect Dis
. 2022 Aug;
76(4):738-740.
PMID: 35913432
Long coronavirus disease (COVID [LC]) constitutes a potential health emergency as millions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections lead to chronic symptoms. We must understand whether vaccines...
7.
Krishna B, Lim E, Mactavous L, Lyons P, Doffinger R, Bradley J, et al.
EBioMedicine
. 2022 Jun;
81:104129.
PMID: 35772216
Background: There is currently no consensus on the diagnosis, definition, symptoms, or duration of COVID-19 illness. The diagnostic complexity of Long COVID is compounded in many patients who were or...
8.
Krishna B, Wass A, Murphy E, OConnor C
Viruses
. 2022 Jun;
14(6).
PMID: 35746751
Human cytomegalovirus (CMV) is a ubiquitous pathogen that latently resides in hematopoietic cells. Latently infected individuals with dysfunctional immune systems often experience CMV reactivation, which can cause devastating disease and...
9.
Elder E, Krishna B, Poole E, Perera M, Sinclair J
J Gen Virol
. 2021 May;
102(5).
PMID: 34042564
Viral latency is an active process during which the host cell environment is optimized for latent carriage and reactivation. This requires control of both viral and host gene promoters and...
10.
Krishna B, Wass A, Dooley A, OConnor C
J Cell Sci
. 2020 Nov;
134(5).
PMID: 33199520
Human cytomegalovirus (HCMV) establishes life-long latent infection in hematopoietic progenitor cells and circulating monocytes in infected individuals. Myeloid differentiation coupled with immune dysregulation leads to viral reactivation, which can cause...