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Rajagopal Varada

Explore the profile of Rajagopal Varada including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 13
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Recent Articles
1.
Sahu A, Shah R, Nashier D, Sharma P, Varada R, Lahry K, et al.
J Bacteriol . 2024 Aug; 206(9):e0025124. PMID: 39171914
Importance: harbors four initiator tRNA (i-tRNA) genes: three of these at and the fourth one at loci. In B, all four genes encode i-tRNA. In K, because of a single-nucleotide...
2.
Kapoor I, Varada R, Aroli S, Varshney U
Microbiology (Reading) . 2019 Sep; 165(11):1219-1232. PMID: 31526453
Nudix hydrolase family proteins hydrolyse toxic by-products of cellular metabolism such as mutagenic nucleoside triphosphates, sugar nucleotides and signalling molecules. We studied the substrate specificities of Nudix hydrolases encoded by...
3.
Shah R, Varada R, Sah S, Shetty S, Lahry K, Singh S, et al.
Nucleic Acids Res . 2019 Jan; 47(4):1908-1919. PMID: 30608556
Initiator tRNAs (i-tRNAs) possess highly conserved three consecutive GC base pairs (GC/GC/GC, 3GC pairs) in their anticodon stems. Additionally, in bacteria and eukaryotic organelles, the amino acid attached to i-tRNA...
4.
Sah S, Shah R, Govindan A, Varada R, Rex K, Varshney U
Microbiology (Reading) . 2018 May; 164(7):982-991. PMID: 29799386
Dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase (PurH) play key roles in maintaining folate pools in cells, and are targets of antimicrobial and anticancer drugs. While the activities...
5.
Agrawal P, Varada R, Sah S, Bhattacharyya S, Varshney U
J Bacteriol . 2018 Jan; 200(6). PMID: 29311276
Bacteria respond to stressful growth conditions through a conserved phenomenon of stringent response mediated by synthesis of stress alarmones ppGpp and pppGpp [referred to as (p)ppGpp]. (p)ppGpp synthesis is known...