Rainer Schreiber
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Explore the profile of Rainer Schreiber including associated specialties, affiliations and a list of published articles.
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Articles
140
Citations
3865
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Recent Articles
1.
Ousingsawat J, Talbi K, Gomez-Martin H, Koy A, Fernandez-Jaen A, Tekgul H, et al.
BMC Med
. 2025 Jan;
23(1):12.
PMID: 39773217
Background: Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TMEM16C), a phospholipid scramblase and ion channel. We previously reported patients...
2.
Ousingsawat J, Schreiber R, Kunzelmann K
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337485
Anoctamin 6 (ANO6, TMEM16F) is a phospholipid (PL) scramblase that moves PLs between both plasma membrane (PM) leaflets and operates as an ion channel. It plays a role in development...
3.
Schreiber R, Cabrita I, Kunzelmann K
Gastro Hep Adv
. 2024 Aug;
1(6):1088-1098.
PMID: 39131261
Background And Aims: Paneth cells play a central role in intestinal innate immune response. These cells are localized at the base of small intestinal crypts of Lieberkuhn. The calcium-activated chloride...
4.
Kunzelmann K, Ousingsawat J, Schreiber R
Cell Calcium
. 2024 Apr;
120:102888.
PMID: 38657371
Plasma membrane localized anoctamin 1, 2 and 6 (TMEM16A, B, F) have been examined in great detail with respect to structure and function, but much less is known about the...
5.
Schreiber R, Ousingsawat J, Kunzelmann K
Cell Calcium
. 2024 Apr;
120:102885.
PMID: 38642428
When activated by increase in intracellular Ca, anoctamins (TMEM16 proteins) operate as phospholipid scramblases and as ion channels. Anoctamin 1 (ANO1) is the Ca-activated epithelial anion-selective channel that is coexpressed...
6.
Ousingsawat J, Centeio R, Reyne N, McCarron A, Cmielewski P, Schreiber R, et al.
Sci Rep
. 2024 Jan;
14(1):1464.
PMID: 38233410
The Ca activated Cl channel TMEM16A (anoctamin 1; ANO1) is expressed in secretory epithelial cells of airways and intestine. Previous studies provided evidence for a role of ANO1 in mucus...
7.
Ousingsawat J, Talbi K, Gomez-Martin H, Koy A, Fernandez-Jaen A, Tekgul H, et al.
Brain
. 2023 Dec;
147(6):1982-1995.
PMID: 38079528
Anoctamin 3 (ANO3) belongs to a family of transmembrane proteins that form phospholipid scramblases and ion channels. A large number of ANO3 variants were identified as the cause of craniocervical...
8.
Ousingsawat J, Centeio R, Schreiber R, Kunzelmann K
Pflugers Arch
. 2023 Nov;
476(2):211-227.
PMID: 37979051
Inflammatory airway diseases like cystic fibrosis, asthma and COVID-19 are characterized by high levels of pulmonary cytokines. Two well-established antiparasitic drugs, niclosamide and ivermectin, are intensively discussed for the treatment...
9.
Salari A, Xiu R, Amiri M, Pallenberg S, Schreiber R, Dittrich A, et al.
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762516
Studies in human colonic cell lines and murine intestine suggest the presence of a Ca-activated anion channel, presumably TMEM16a. Is there a potential for fluid secretion in patients with severe...
10.
Kunzelmann K, Ousingsawat J, Kraus A, Park J, Marquardt T, Schreiber R, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686084
The Cl-transporting proteins CFTR, SLC26A9, and anoctamin (ANO1; ANO6) appear to have more in common than initially suspected, as they all participate in the pathogenic process and clinical outcomes of...