Rainer Lehmann
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Explore the profile of Rainer Lehmann including associated specialties, affiliations and a list of published articles.
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118
Citations
2624
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Recent Articles
1.
Kopczynski D, Ejsing C, McDonald J, Bamba T, Baker E, Bertrand-Michel J, et al.
J Lipid Res
. 2024 Aug;
65(9):100621.
PMID: 39151590
The rapid increase in lipidomic studies has led to a collaborative effort within the community to establish standards and criteria for producing, documenting, and disseminating data. Creating a dynamic easy-to-use...
2.
Rubenzucker S, Manke M, Lehmann R, Assinger A, Borst O, Ahrends R
Anal Chem
. 2024 May;
96(23):9643-9652.
PMID: 38795073
Signaling lipids are key players in cellular processes. Despite their importance, no method currently allows their comprehensive monitoring in one analytical run. Challenges include a wide dynamic range, isomeric and...
3.
Zheng S, Zhou L, Hoene M, Peter A, Birkenfeld A, Weigert C, et al.
Metabolites
. 2023 Oct;
13(10).
PMID: 37887386
The gut microbiome is of tremendous relevance to human health and disease, so it is a hot topic of omics-driven biomedical research. However, a valid identification of gut microbiota-associated molecules...
4.
Troppmair N, Kopczynski D, Assinger A, Lehmann R, Coman C, Ahrends R
Anal Chem
. 2023 Oct;
95(41):15227-15235.
PMID: 37782305
Quantitative sphingolipid analysis is crucial for understanding the roles of these bioactive molecules in various physiological and pathological contexts. Molecular sphingolipid species are typically quantified using sphingoid base-derived fragments relative...
5.
Sandforth A, von Schwartzenberg R, Arreola E, Hanson R, Sancar G, Katzenstein S, et al.
Lancet Diabetes Endocrinol
. 2023 Sep;
11(11):798-810.
PMID: 37769677
Background: Remission of type 2 diabetes can occur as a result of weight loss and is characterised by liver fat and pancreas fat reduction and recovered insulin secretion. In this...
6.
Maurer J, Zhao X, Irmler M, Gudiksen A, Pilmark N, Li Q, et al.
Am J Physiol Cell Physiol
. 2023 Sep;
325(4):C1131-C1143.
PMID: 37694284
Metformin-induced glycolysis and lactate production can lead to acidosis as a life-threatening side effect, but slight increases in blood lactate levels in a physiological range were also reported in metformin-treated...
7.
Junger S, Hoene M, Shipkova M, Danzl G, Schoberl C, Peter A, et al.
J Mass Spectrom Adv Clin Lab
. 2023 Aug;
30:1-9.
PMID: 37583571
Background: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a sensitive method with high specificity. However, its routine use in the clinical laboratory is hampered by its high complexity and lack of...
8.
Wang Q, Hoene M, Hu C, Fritsche L, Ahrends R, Liebisch G, et al.
J Lipid Res
. 2023 Apr;
64(6):100378.
PMID: 37087100
Reliability, robustness, and interlaboratory comparability of quantitative measurements is critical for clinical lipidomics studies. Lipids' different ex vivo stability in blood bears the risk of misinterpretation of data. Clear recommendations...
9.
Hoene M, Zhao X, Machann J, Birkenfeld A, Heni M, Peter A, et al.
Metabolites
. 2023 Jan;
13(1).
PMID: 36676940
Physical exercise is a powerful measure to prevent cardiometabolic diseases. However, the individual response to lifestyle interventions is variable and cannot, to date, be predicted. N-Lactoylphenylalanine (Lac-Phe) produced during exercise...
10.
Li Z, Zhang Y, Hoene M, Fritsche L, Zheng S, Birkenfeld A, et al.
Front Endocrinol (Lausanne)
. 2022 Aug;
13:935016.
PMID: 35909528
Aims/hypothesis: Large-scale prediabetes screening is still a challenge since fasting blood glucose and HbA as the long-standing, recommended analytes have only moderate diagnostic sensitivity, and the practicability of the oral...