Journal of Mass Spectrometry and Advances in the Clinical Lab

Overview

Journal of Mass Spectrometry and Advances in the Clinical Lab is a scientific journal, published since 2021 in English. The journal's country of origin is Netherlands and its primary focus area is general medicine.

Details

Abbr. J Mass Spectrom Adv Clin Lab

Start 2021

End Continuing

p-ISSN 2667-1468

e-ISSN 2667-145X

Country Netherlands

Language English

Specialty General Medicine

Metrics

h-index / Ranks: 13168 16

SJR / Ranks: 5650 762

CiteScore / Ranks: 7225 3.70

Recent Articles

High-resolution mass spectrometry measurement of N-terminal carbamylated hemoglobin as a potential marker for chronic diseases with elevated blood urea levels

Chen F, Yeung P, Wong C, Luo R

J Mass Spectrom Adv Clin Lab . 2025 Mar; 35:8-13. PMID: 40034798

Introduction: N-terminal carbamylated hemoglobin (CarHb) reflects long-term blood urea levels and has potential as a marker for chronic kidney disease (CKD) and other chronic conditions with elevated blood urea levels....

A liquid chromatography-high-resolution mass spectrometry method for separation and identification of hemoglobin variant subunits with mass shifts less than 1 Da

Chen A, Aquino R, Vidal H, Wong C, Luo R

J Mass Spectrom Adv Clin Lab . 2025 Feb; 35:1-7. PMID: 39995439

Background: Identification of hemoglobin (Hb) variants is valuable in clinical testing. A common issue with conventional methods for identifying Hb variants is their subpar ability to provide structural breakdowns of...

Development and clinical utility of an ultra performance liquid chromatography - tandem mass spectrometry assay for monitoring omadacycline and tigecycline in severe bacterial infections

Wang C, Luo B, Liu W, Jia C, Chen H, Ma J, et al.

J Mass Spectrom Adv Clin Lab . 2024 Dec; 34:46-54. PMID: 39649553

Objective: We aimed to develop a rapid, simple, and precise ultra performance liquid chromatography - tandem mass spectrometry (UPLC-MS/MS) technique for simultaneous measurement of omadacycline (OMA) and tigecycline (TGC) in...

Tandem mass spectrometry of serum cholestanoic (C) acids - Typical concentration ranges and application to the study of peroxisomal biogenesis disorders

Zhang W, Narvaez Rivas M, Setchell K

J Mass Spectrom Adv Clin Lab . 2024 Nov; 34:34-43. PMID: 39584149

Background: Primary bile acid synthesis is impaired in peroxisomal disorders, leading to the accumulation of long-chain bile acids, specifically dihydroxycholestanoic and trihydroxycholestanoic acids. Quantification of the diastereoisomers of these C...

Research letter: Pilot study of a prototype fully automated mass spectrometry system for routine clinical laboratory use

Vogeser M, Habler K, Reuter A, Schneider-Thauern C

J Mass Spectrom Adv Clin Lab . 2024 Nov; 34:44-45. PMID: 39584148

No abstract available.

Development and validation of an LC-MS/MS method for highly concentrated tacrolimus and cyclosporine samples prepared from pharmaceutical products to assess drug loss from feeding tubes

Xiao Y, Gabra M, Leung E

J Mass Spectrom Adv Clin Lab . 2024 Nov; 34:28-33. PMID: 39502200

Introduction: Tacrolimus and cyclosporine are common immunosuppressants utilized post-organ transplantation to manage allograft rejection. Both have narrow therapeutic indices and are frequently measured to support dose adjustments. Although nasogastric tubes...

Liquid chromatography-mass spectrometric method for the simultaneous analysis of branched-chain amino acids and their ketoacids from dried blood spot as secondary analytes for the detection of maple syrup urine disease

Raveendran A, Gupta A, Lewis L, Prabhu K, Moorkoth S

J Mass Spectrom Adv Clin Lab . 2024 Nov; 34:8-20. PMID: 39492949

Background: Maple syrup urine disease (MSUD) is an aminoacidopathy caused by a defective branched-chain alpha-ketoacid dehydrogenase complex, leading to the accumulation of branched-chain amino acids (BCAAs) and their respective keto...

Method validation of an inductively coupled plasma mass spectrometry (ICP-MS) assay for the analysis of magnesium, copper and zinc in red blood cells

Bithi N, Ricks D, Walker B, Law C, Johnson-Davis K

J Mass Spectrom Adv Clin Lab . 2024 Oct; 34:21-27. PMID: 39469428

Background: Laboratory measurements of trace elements such as magnesium (Mg), copper (Cu), and zinc (Zn) in red blood cells (RBCs) are essential for assessing nutritional status and diagnosing metal toxicity....

Rapid and sensitive liquid chromatographic-tandem mass spectrometric methods for the quantitation of dolutegravir in human plasma and breast milk

Rackow A, Pandey A, Price A, Marzinke M

J Mass Spectrom Adv Clin Lab . 2024 Oct; 34:1-7. PMID: 39429949

Background: Dolutegravir (DTG) is part of a first-line antiretroviral therapy (ART) for HIV management in drug-naïve individuals and is recommended for the treatment of HIV during pregnancy. Robust analytical tools...

10.

Understanding isotopes, isomers, and isobars in mass spectrometry

Habler K, Rexhaj A, Adling-Ehrhardt M, Vogeser M

J Mass Spectrom Adv Clin Lab . 2024 Sep; 33:49-54. PMID: 39279892

Mass spectrometry (MS) is a versatile analytical tool used in various fields such as biochemistry, pharmacology, omics, and clinical analysis for determining and quantifying compounds based on their molecular mass...