Rainer Bischoff
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Explore the profile of Rainer Bischoff including associated specialties, affiliations and a list of published articles.
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210
Citations
2663
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Recent Articles
1.
Rower C, Olaleye O, Bischoff R, Glocker M
Biomolecules
. 2024 Jan;
14(1).
PMID: 38254624
Intact Transition Epitope Mapping-One-step Non-covalent force Exploitation (ITEM-ONE) analysis reveals an assembled epitope on the surface of Pertuzumab, which is recognized by the anti-Pertuzumab affimer 00557_709097. It encompasses amino acid...
2.
Russo S, Kwiatkowski M, Wolters J, Gerding A, Hermans J, Govorukhina N, et al.
J Leukoc Biol
. 2023 Oct;
115(3):435-449.
PMID: 37811856
Macrophages are key immune cells that can adapt their metabolic phenotype in response to different stimuli. Lysine deacetylases are important enzymes regulating inflammatory gene expression and lysine deacetylase inhibitors have...
3.
Hermans J, Alipour Najmi A, Permentier H, Bischoff R
Talanta
. 2023 Jul;
266(Pt 1):124928.
PMID: 37454516
Flow cell reactors used for catalyst development and applications are upcoming due to their small environmental and economic footprint. Online microflow reactor coupling with mass spectrometry (MS) opens new possibilities...
4.
Vasse G, Russo S, Barcaru A, Oun A, Dolga A, van Rijn P, et al.
Sci Rep
. 2023 Apr;
13(1):5670.
PMID: 37024614
Idiopathic pulmonary fibrosis is a progressive lung disease that causes scarring and loss of lung function. Macrophages play a key role in fibrosis, but their responses to altered morphological and...
5.
Olaleye O, Graf C, Spanov B, Govorukhina N, Groves M, van de Merbel N, et al.
J Am Soc Mass Spectrom
. 2023 Mar;
34(4):775-783.
PMID: 36960982
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is a method to probe the solvent accessibility and conformational dynamics of a protein or a protein-ligand complex with respect to exchangeable amide hydrogens. Here,...
6.
Bekker N, van Pijkeren A, Wolters J, Sanchez Brotons A, Guryev V, Woldhuis R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Feb;
324(4):L521-L535.
PMID: 36808722
Lung fibroblasts are implicated in abnormal tissue repair in chronic obstructive pulmonary disease (COPD). The exact mechanisms are unknown and comprehensive analysis comparing COPD- and control fibroblasts is lacking. The...
7.
Spanov B, Olaleye O, Mesurado T, Govorukhina N, Jungbauer A, van de Merbel N, et al.
Anal Chem
. 2023 Feb;
95(8):3951-3958.
PMID: 36795375
Pertuzumab is a monoclonal antibody used for the treatment of HER2-positive breast cancer in combination with trastuzumab. Charge variants of trastuzumab have been extensively described in the literature; however, little...
8.
Klont F, Olaleye O, Bischoff R
Methods Mol Biol
. 2023 Feb;
2628:221-233.
PMID: 36781789
Liquid chromatography (LC) coupled to mass spectrometry (MS) is increasingly used for quantification of proteins in blood. This development is prompted by ongoing improvements in detection sensitivities of LC-MS instruments...
9.
Sleumer B, Zwerwer J, van Faassen M, Vos M, Bischoff R, Kema I, et al.
Clin Chem Lab Med
. 2023 Feb;
61(7):1266-1274.
PMID: 36773321
Objectives: Sex hormone binding globulin (SHBG) is a hormone binding protein which plays an important role in regulating the transport and availability of biologically active androgens and estradiol to target...
10.
van Pijkeren A, Egger A, Hotze M, Zimmermann E, Kipura T, Grander J, et al.
J Proteome Res
. 2023 Feb;
22(3):951-966.
PMID: 36763818
Proteomics and metabolomics are essential in systems biology, and simultaneous proteo-metabolome liquid-liquid extraction (SPM-LLE) allows isolation of the metabolome and proteome from the same sample. Since the proteome is present...