Rahul Roychoudhuri
Overview
Explore the profile of Rahul Roychoudhuri including associated specialties, affiliations and a list of published articles.
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66
Citations
4517
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Recent Articles
1.
Yang J, Yamashita-Kanemaru Y, Morris B, Contursi A, Trajkovski D, Xu J, et al.
Nature
. 2025 Mar;
PMID: 40044852
Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally. Metastasizing cancer cells are uniquely vulnerable to...
2.
Sardar P, Beresford-Jones B, Xia W, Shabana O, Suyama S, Ramos R, et al.
Nat Microbiol
. 2025 Feb;
10(3):795-807.
PMID: 39929976
The gut microbiome modulates immunotherapy treatment responses, and this may explain why immune checkpoint inhibitors, such as anti-PD-1, are only effective in some patients. Previous studies correlated lipopolysaccharide (LPS)-producing gut...
3.
Courreges C, Davenport E, Bilanges B, Rebollo-Gomez E, Hukelmann J, Schoenfelder P, et al.
Front Immunol
. 2024 Dec;
15:1374621.
PMID: 39664390
Regulatory T (Treg) cells are essential for the maintenance of immunological tolerance, yet the molecular components required for their maintenance and effector functions remain incompletely defined. Inactivation of VPS34 in...
4.
Scirgolea C, Sottile R, De Luca M, Susana A, Carnevale S, Puccio S, et al.
Nat Immunol
. 2024 Aug;
25(10):1845-1857.
PMID: 39198631
CD8 T cells control tumors but inevitably become dysfunctional in the tumor microenvironment. Here, we show that sodium chloride (NaCl) counteracts T cell dysfunction to promote cancer regression. NaCl supplementation...
5.
Stockis J, Yip T, Moreno-Vicente J, Burton O, Samarakoon Y, Schuijs M, et al.
Sci Immunol
. 2024 Jul;
9(97):eadl1903.
PMID: 39028828
Regulatory T cells (T) control adaptive immunity and restrain type 2 inflammation in allergic disease. Interleukin-33 promotes the expansion of tissue-resident T and group 2 innate lymphoid cells (ILC2s); however,...
6.
Imianowski C, Kuo P, Whiteside S, von Linde T, Wesolowski A, Conti A, et al.
Cancer Res Commun
. 2024 Jul;
4(8):2045-2057.
PMID: 38995700
Significance: The bispecific antibody FS120, an immunotherapy currently being tested in the clinic, partially functions by inducing anti-tumor activity of Tregs, which results in tumor rejection.
7.
Lise V, Malenica I, Roychoudhuri R, Lugli E
Cancer Cell
. 2024 Jul;
42(7):1152-1154.
PMID: 38981434
In this issue of Cancer Cell, Espinosa-Carrasco et al. show that the efficacy of cancer immunotherapies depends upon the formation of intratumoral immune triads between antigen-presenting cells and antigen-specific CD4...
8.
Takahashi M, So T, Chamberlain-Evans V, Hughes R, Yam-Puc J, Kania K, et al.
Sci Immunol
. 2024 May;
9(95):eade2094.
PMID: 38787961
Immunotherapy advances have been hindered by difficulties in tracking the behaviors of lymphocytes after antigen signaling. Here, we assessed the behavior of T cells active within tumors through the development...
9.
Baird T, Roychoudhuri R
J Comput Biol
. 2024 Mar;
31(3):229-240.
PMID: 38436570
Most tools for analyzing large gene expression datasets, including The Cancer Genome Atlas (TCGA), have focused on analyzing the expression of individual genes or inference of the abundance of specific...
10.
Lee C, Kennedy B, Richoz N, Dean I, Tuong Z, Gaspal F, et al.
Nat Commun
. 2024 Jan;
15(1):682.
PMID: 38267413
Tumour dendritic cells (DCs) internalise antigen and upregulate CCR7, which directs their migration to tumour-draining lymph nodes (dLN). CCR7 expression is coupled to an activation programme enriched in regulatory molecule...