Raga Krishnakumar
Overview
Explore the profile of Raga Krishnakumar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
1714
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Krishnakumar R, Chen A, Pantovich M, Danial M, Parchem R, Labosky P, et al.
Cell Stem Cell
. 2018 Aug;
23(2):306-307.
PMID: 30075131
No abstract available.
12.
Chen A, Liu A, Krishnakumar R, Freimer J, Deveale B, Blelloch R
Cell Stem Cell
. 2018 Jul;
23(2):226-238.e4.
PMID: 30017589
The enhancer landscape of pluripotent stem cells undergoes extensive reorganization during early mammalian development. The functions and mechanisms behind such reorganization, however, are unclear. Here, we show that the transcription...
13.
Krishnakumar R, Sinha A, Bird S, Jayamohan H, Edwards H, Schoeniger J, et al.
Sci Rep
. 2018 Feb;
8(1):3159.
PMID: 29453452
Emerging sequencing technologies are allowing us to characterize environmental, clinical and laboratory samples with increasing speed and detail, including real-time analysis and interpretation of data. One example of this is...
14.
Freimer J, Krishnakumar R, Cook M, Blelloch R
Curr Biol
. 2018 Jan;
28(2):296-302.e3.
PMID: 29307557
Mouse oocyte maturation, fertilization, and reprogramming occur in the absence of transcription, and thus, changes in mRNA levels and translation rate are regulated through post-transcriptional mechanisms [1]. Surprisingly, microRNA function,...
15.
Krishnakumar R, Chen A, Pantovich M, Danial M, Parchem R, Labosky P, et al.
Cell Stem Cell
. 2016 Jan;
18(1):104-17.
PMID: 26748757
Early development is governed by the ability of pluripotent cells to retain the full range of developmental potential and respond accurately to developmental cues. This property is achieved in large...
16.
Parchem R, Ye J, Judson R, LaRussa M, Krishnakumar R, Blelloch A, et al.
Cell Stem Cell
. 2014 Mar;
14(5):617-31.
PMID: 24630794
Ectopic expression of specific factors such as Oct4, Sox2, and Klf4 (OSK) is sufficient to reprogram somatic cells into induced pluripotent stem cells (iPSCs). In this study, we examine the...
17.
Luo X, Chae M, Krishnakumar R, Danko C, Kraus W
BMC Genomics
. 2014 Feb;
15:155.
PMID: 24564208
Background: Defining cell type-specific transcriptomes in mammals can be challenging, especially for unannotated regions of the genome. We have developed an analytical pipeline called groHMM for annotating primary transcripts using...
18.
Krishnakumar R, Blelloch R
Curr Opin Genet Dev
. 2013 Aug;
23(5):548-55.
PMID: 23948105
Cells are constantly changing their state of equilibrium in response to internal and external stimuli. These changes in cell identity are driven by highly coordinated modulation of gene expression. This...
19.
Zhang T, Berrocal J, Yao J, DuMond M, Krishnakumar R, Ruhl D, et al.
J Biol Chem
. 2012 Feb;
287(15):12405-16.
PMID: 22334709
NMNAT-1 and PARP-1, two key enzymes in the NAD(+) metabolic pathway, localize to the nucleus where integration of their enzymatic activities has the potential to control a variety of nuclear...
20.
Krishnakumar R, Kraus W
Mol Cell
. 2010 Sep;
39(5):736-49.
PMID: 20832725
PARP-1 is an abundant nuclear enzyme that regulates gene expression, although the underlying mechanisms are unclear. We examined the interplay between PARP-1, histone 3 lysine 4 trimethylation (H3K4me3), and linker...