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Rafael Leon-Lopez

Explore the profile of Rafael Leon-Lopez including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 73
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Recent Articles
1.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, et al.
Genome Med . 2024 Jan; 16(1):6. PMID: 38184654
No abstract available.
2.
Trigo-Rodriguez M, Carcel S, Navas A, Espindola-Gomez R, Garrido-Gracia J, Esteban Moreno M, et al.
Open Forum Infect Dis . 2023 Apr; 10(4):ofad133. PMID: 37035487
Background: The Clinical Trial of Sarilumab in Adults With COVID-19 (SARICOR) showed that patients with coronavirus disease 2019 (COVID-19) pneumonia and increased levels of interleukin (IL)-6 might benefit from blockade...
3.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, et al.
Genome Med . 2023 Apr; 15(1):22. PMID: 37020259
Background: We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN,...
4.
Matuozzo D, Talouarn E, Marchal A, Manry J, Seeleuthner Y, Zhang Y, et al.
medRxiv . 2022 Nov; PMID: 36324795
Background: We previously reported inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity in 1-5% of unvaccinated patients with life-threatening COVID-19, and auto-antibodies against type I IFN in...
5.
Bergin S, Calvert S, Farley J, Sun J, Chiswell K, Dieperink W, et al.
Open Forum Infect Dis . 2022 Jul; 9(7):ofac231. PMID: 35836748
Background: The prospective identification of patients at high risk for hospital-acquired/ventilator-associated bacterial pneumonia may improve clinical trial feasibility and foster antibacterial development. In a prior study conducted in the United...
6.
Fernandez-Martinez N, Carcel-Fernandez S, De la Fuente-Martos C, Ruiz-Montero R, Guzman-Herrador B, Leon-Lopez R, et al.
Int J Environ Res Public Health . 2022 Feb; 19(3). PMID: 35162062
Multidrug-resistant Gram-negative bacteria (MDR-GNB) are microorganisms that have acquired resistance to extended-spectrum antibacterials and constitute an emerging threat to public health. Although carriers are an important source of transmission in...
7.
Merchante N, Carcel S, Garrido-Gracia J, Trigo-Rodriguez M, Esteban Moreno M, Leon-Lopez R, et al.
Antimicrob Agents Chemother . 2021 Dec; 66(2):e0210721. PMID: 34902262
The objective of this study was to investigate the efficacy and safety of early treatment with sarilumab, added to standard of care (SOC), in hospitalized adults with COVID-19. Methods included...
8.
Morales-Cane I, Lopez-Soto P, Valverde-Leon M, Moral-Arroyo J, Leon-Lopez R, Rodriguez-Borrego M
Int J Nurs Pract . 2020 May; 26(5):e12853. PMID: 32453480
Aims: Our study examined factors influencing the development of healthcare-associated infections in the intensive care unit (ICU) of a tertiary hospital in southern Spain. Background: Healthcare-associated infections are a frequent...
9.
Llompart-Pou J, Chico-Fernandez M, Sanchez-Casado M, Alberdi-Odriozola F, Guerrero-Lopez F, Mayor-Garcia M, et al.
Injury . 2016 Oct; 47 Suppl 3:S61-S65. PMID: 27692109
Background: Injury patterns may differ in trauma patients when age is considered. This information is relevant in the management of trauma patients and for planning preventive measures. Methods: We included...