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Rachel Chen

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Articles 59
Citations 487
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Recent Articles
1.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms J, Niezen S, Delorey T, et al.
Genome Biol . 2025 Mar; 26(1):56. PMID: 40087773
Background: The molecular underpinnings of organ dysfunction in severe COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function,...
2.
Huang J, Luo S, Shen J, Lee M, Chen R, Ma S, et al.
Oncogene . 2025 Mar; PMID: 40057606
Disrupted cellular polarity (DCP) is a hallmark of solid cancer, the malignant disease of epithelial tissues, which occupies ~90% of all human cancers. DCP has been identified to affect not...
3.
Wang D, Chen R, Anjum N, Ke C
Nanotechnology . 2024 Nov; 36(6). PMID: 39607034
Controlling the thermal expansion of ceramic materials is important for many of their applications that involve high-temperature processing and/or working conditions. In this study, we investigate the thermal expansion properties...
4.
Sbaraini N, Crombie A, Kalaitzis J, Vuong D, Bracegirdle J, Windsor F, et al.
Chem Sci . 2024 Oct; PMID: 39479171
Depsides have garnered substantial interest due to the diverse biological activities exhibited by members of this class. Among these are the antibacterial aquastatins, glycosylated heteromeric depsides formed through the condensation...
5.
Park M, Le Berichel J, Hamon P, Wilk C, Belabed M, Yatim N, et al.
Science . 2024 Sep; 386(6720):eadn0327. PMID: 39236155
Age is a major risk factor for cancer, but how aging impacts tumor control remains unclear. In this study, we establish that aging of the immune system, regardless of the...
6.
Bulcock B, Chen R, Lacey E, Chooi Y, Flematti G
J Nat Prod . 2024 Aug; 87(8):2101-2109. PMID: 39129216
Tertiary and allylic hydroxyl groups readily eliminate water during positive ion mode mass spectrometry and may show similar NMR spectra to their corresponding ethers. In a routine structure elucidation workflow,...
7.
Giotti B, Dolasia K, Zhao W, Cai P, Sweeney R, Merritt E, et al.
Cancer Discov . 2024 Jul; 14(11):2262-2278. PMID: 38959428
Immunotherapies have shown great promise in pleural mesothelioma (PM), yet most patients still do not achieve significant clinical response, highlighting the importance of improving the understanding of the tumor microenvironment...
8.
Crombie A, Kalaitzis J, Chen R, Vuong D, Lacey A, Lacey E, et al.
J Antibiot (Tokyo) . 2024 Jun; 77(10):639-646. PMID: 38926492
Two new depside antibiotics, geministatins A (1) and B (2), were isolated from the fungus Austroacremonium gemini MST-FP2131 (Sordariomycetes, Ascomycota), which was recovered from rotting wood in the wet tropics...
9.
Pilcher W, Yao L, Gonzalez-Kozlova E, Pita-Juarez Y, Karagkouni D, Acharya C, et al.
bioRxiv . 2024 May; PMID: 38798338
Multiple Myeloma (MM) remains incurable despite advances in treatment options. Although tumor subtypes and specific DNA abnormalities are linked to worse prognosis, the impact of immune dysfunction on disease emergence...
10.
Chen P, Chen R, LaPierre N, Chen Z, Mefford J, Marcus E, et al.
Cell Genom . 2024 May; 4(5):100545. PMID: 38697120
Knowing the genes involved in quantitative traits provides an entry point to understanding the biological bases of behavior, but there are very few examples where the pathway from genetic locus...