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R Verger

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Articles 185
Citations 1661
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Recent Articles
11.
Tiss A, Ransac S, Lengsfeld H, Hadvary P, Cagna A, Verger R
Chem Phys Lipids . 2001 Jul; 111(1):73-85. PMID: 11438285
The surface behaviour of two bile salts, sodium deoxycholate (NaDC) and sodium taurodeoxycholate (NaTDC), as well as that of tetrahydrolipstatin (THL), a potent gastrointestinal lipase inhibitor, was studied at air/water...
12.
Chiou A, Verger R, Kokotos G
Lipids . 2001 Jul; 36(5):535-42. PMID: 11432468
Synthetic routes to primary and N-alkyl alpha-keto amides are presented in this paper. Primary alpha-keto amides may be prepared by using an aldehyde as starting material. Commercially available alpha-keto acids...
13.
Kotsovolou S, Chiou A, Verger R, Kokotos G
J Org Chem . 2001 Jun; 66(3):962-7. PMID: 11430119
A novel class of potent human gastric lipase inhibitors, bis-2-oxo amide triacylglycerol analogues, was developed. These analogues of the natural substrate of lipases were prepared starting from 1,3-diaminopropan-2-ol. They were...
14.
Tiss A, Carriere F, Verger R
Anal Biochem . 2001 Jun; 294(1):36-43. PMID: 11412003
We investigated the surface behavior of gum Arabic (GA) as well as its effects on the lipolytic activity of human pancreatic lipase (HPL) and Humicola lanuginosa lipase (HLL), using emulsions...
15.
Carriere F, Renou C, Ransac S, Lopez V, De Caro J, Ferrato F, et al.
Am J Physiol Gastrointest Liver Physiol . 2001 Jun; 281(1):G16-28. PMID: 11408251
The inhibition of digestive lipases by the antiobesity drug Orlistat along with lipolysis levels and fecal fat excretion were measured in healthy humans. Orlistat was found to be a powerful...
16.
Beisson F, Ferte N, Bruley S, Voultoury R, Verger R, Arondel V
Biochim Biophys Acta . 2001 Mar; 1531(1-2):47-58. PMID: 11278171
Plant seeds store triacylglycerols (TAGs) in intracellular organelles called oil-bodies or oleosomes, which consist of oil droplets covered by a coat of phospholipids and proteins. During seed germination, the TAGs...
17.
Beisson F, Aoubala M, Marull S, Voultoury R, Verger R, Arondel V
Anal Biochem . 2001 Mar; 290(2):179-85. PMID: 11237319
The enzymes secreted in the intercellular spaces of stratum corneum (SC), the outermost layer of the epidermis, are thought to be involved in normal desquamation and skin barrier function. Their...
18.
Abergel C, Abousalham A, Chenivesse S, Riviere M, Verger R
Acta Crystallogr D Biol Crystallogr . 2001 Feb; 57(Pt 2):320-2. PMID: 11173493
The plant phospholipase D (PLD) is considered to be a key enzyme involved in various physiological processes such as signal transduction and membrane metabolism. Crystals of the PLD protein from...
19.
Beisson F, Arondel V, Verger R
Biochem Soc Trans . 2001 Feb; 28(6):773-5. PMID: 11171203
A low lipase activity from a crude extract of Arabidopsis seedlings was assayed using three sensitive methods (radiolabelled triacylglycerols, commercial resorufin ester and triacylglycerols containing the naturally fluorescent parinaric acid...
20.
Kokotos G, Verger R, Chiou A
Chemistry . 2000 Dec; 6(22):4211-7. PMID: 11128286
A general method for the synthesis of chiral 2-oxo amide triacylglycerol analogues, from (R)- or (S)-3-aminopropane-1,2-diol, was developed. These novel inhibitors of digestive lipases are analogues of the triacylglycerol molecule,...