R T Gazzinelli
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Explore the profile of R T Gazzinelli including associated specialties, affiliations and a list of published articles.
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Articles
98
Citations
4781
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Recent Articles
1.
Andrade W, Silva A, Alves V, Salgado A, Melo M, Andrade H, et al.
Genes Immun
. 2010 Jan;
11(6):447-57.
PMID: 20090772
Guanine-nucleotide exchange factors (GEFs) stimulate the intrinsic GDP/GTP exchange activity of Ras and promote the formation of active Ras-GTP, which in turn controls diverse signalling networks important for the regulation...
2.
Gutierrez F, Guedes P, Gazzinelli R, Silva J
Parasite Immunol
. 2009 Oct;
31(11):673-85.
PMID: 19825107
Chagas disease (CD) is caused by the infection with the protozoan haemoflagellate Trypanosoma cruzi. This disease is still a great menace to public health, and is largely neglected as it...
3.
Agero U, Mesquita L, Neves B, Gazzinelli R, Mesquita O
Microsc Res Tech
. 2004 Dec;
65(3):159-65.
PMID: 15605417
Transparent objects (phase objects) are not visible in a standard brightfield optical microscope. In order to see such objects the most used technique is phase-contrast microscopy. In phase-contrast microscopy the...
4.
Agero U, Monken C, Ropert C, Gazzinelli R, Mesquita O
Phys Rev E Stat Nonlin Soft Matter Phys
. 2003 Jun;
67(5 Pt 1):051904.
PMID: 12786175
Phase objects can become visible by slightly defocusing an optical microscope, a technique seldom used as a useful tool. We revisited the theory of defocusing and apply it to our...
5.
Ramos M, Rabelo F, Duarte T, Gazzinelli R, Alvarez-Leite J
Braz J Med Biol Res
. 2002 Feb;
35(2):161-73.
PMID: 11847519
We demonstrated that 4 mM butyrate induces apoptosis in murine peritoneal macrophages in a dose- and time-dependent manner as indicated by studies of cell viability, flow cytometric analysis of annexin-V...
6.
Michailowsky V, Silva N, Rocha C, Vieira L, Lannes-Vieira J, Gazzinelli R
Am J Pathol
. 2001 Nov;
159(5):1723-33.
PMID: 11696433
The role of cytokines in the control of tissue parasitism and pathogenesis of experimental Chagas' disease was investigated. Wild-type and different cytokine as well as inducible nitric oxide synthase (iNOS)...
7.
Almeida I, Gazzinelli R
J Leukoc Biol
. 2001 Oct;
70(4):467-77.
PMID: 11590183
A strong activation of macrophages is observed during acute infection with Trypanosoma cruzi. Little is known, however, about the parasite molecules that are responsible for this early activation of innate...
8.
Dos Santos P, Roffe E, Santiago H, Torres R, MARINO A, Paiva C, et al.
Microbes Infect
. 2001 Oct;
3(12):971-84.
PMID: 11580984
The determinants of the prevalence of CD8(+) T cells in the inflamed myocardium of Trypanosoma cruzi-infected patients and experimental animals are undefined. Using C3H/He mice infected with the Colombiana strain...
9.
de Magalhaes J, Andrade A, Silva P, Sousa L, Ropert C, Ferreira P, et al.
J Biol Chem
. 2001 Jul;
276(42):38353-60.
PMID: 11459835
Vaccinia virus (VV) triggers a mitogenic signal at an early stage of infection. VV-induced proto-oncogene c-fos mRNA with kinetics paralleling that stimulated by serum. The VV virokine, or vaccinia virus...
10.
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
Campos M, Almeida I, Takeuchi O, Akira S, Valente E, Procopio D, et al.
J Immunol
. 2001 Jun;
167(1):416-23.
PMID: 11418678
Glycosylphosphatidylinositol (GPI) anchors and glycoinositolphospholipids (GIPLs) from parasitic protozoa have been shown to exert a wide variety of effects on cells of the host innate immune system. However, the receptor(s)...