R Sehmi
Overview
Explore the profile of R Sehmi including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
482
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Recent Articles
1.
MITCHELL P, Salter B, Oliveria J, El-Gammal A, Tworek D, Smith S, et al.
Clin Exp Allergy
. 2016 Dec;
47(3):331-338.
PMID: 27928844
Background: Glucagon-like peptide-1 (GLP-1) and its receptor are part of the incretin family of hormones that regulate glucose metabolism. GLP-1 also has immune modulatory roles. Objectives: To measure the expression...
2.
Sehmi R, Smith S, Kjarsgaard M, Radford K, Boulet L, Lemiere C, et al.
Clin Exp Allergy
. 2015 Dec;
46(6):793-802.
PMID: 26685004
Background: In severe asthmatics with persistent airway eosinophilia, blockade of interleukin-5 has significant steroid-sparing effects and attenuates blood and sputum eosinophilia. The contribution of local maturational processes of progenitors within...
3.
Neighbour H, Boulet L, Lemiere C, Sehmi R, Leigh R, Sousa A, et al.
Clin Exp Allergy
. 2013 Nov;
44(4):508-16.
PMID: 24286456
Background: Several chemokines, notably eotaxin, mediate the recruitment of eosinophils into tissues via the CCR3 receptor. Objective: In this study, we investigated the role of CCR3 agonists in asthma by...
4.
Sehmi R, Angelopoulos L
J Obstet Gynaecol
. 2012 Dec;
33(1):88.
PMID: 23259891
No abstract available.
5.
Punia N, Smith S, Thomson J, Irshad A, Nair P, Sehmi R
Clin Exp Allergy
. 2011 Nov;
42(2):255-64.
PMID: 22092872
Background: Lung-homing of progenitor cells is associated with inflammatory and remodelling changes in asthma. Factors that modulate the increased traffic of progenitor cells to the site of inflammation in asthma...
6.
Imaoka H, Campbell H, Babirad I, Watson R, Mistry M, Sehmi R, et al.
Clin Exp Allergy
. 2011 Jul;
41(12):1740-6.
PMID: 21762225
Background: TPI ASM8 contains two modified phosphorothioate antisense oligonucleotides (AON), one targeting the common beta chain (βc) of the IL-3/IL-5/GM-CSF receptors and the other targeting the chemokine receptor CCR3. Inhalation...
7.
DOYLE T, Ellis R, Park H, Inman M, Sehmi R
Eur Respir J
. 2010 Nov;
38(3):679-87.
PMID: 21071475
Asthmatic responses are associated with the lung homing of bone marrow (BM)-derived progenitors implicated as effectors of disease pathology. Studies have shown that increases in lung extracted vascular endothelial progenitor...
8.
Fanat A, Thomson J, Radford K, Nair P, Sehmi R
Clin Exp Allergy
. 2009 May;
39(7):1009-17.
PMID: 19438586
Introduction: Human airway smooth muscle (HASM) cells in culture synthesize cytokines and chemokines that may orchestrate the tissue homing and in situ differentiation of haemopoietic progenitor cells from the peripheral...
9.
10.
Sehmi R, Baatjes A, Denburg J
Curr Drug Targets Inflamm Allergy
. 2003 Oct;
2(4):271-8.
PMID: 14561146
Eosinophilic infiltration is a cardinal feature of allergic inflammation; based upon its biological actions, the eosinophil has assumed the role as the principal inflammatory cell in asthma. In assessing the...