R Sehmi
Overview
Explore the profile of R Sehmi including associated specialties, affiliations and a list of published articles.
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31
Citations
482
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Recent Articles
11.
Lundahl J, Sehmi R, Moshfegh A, Hayes L, Howie K, Upham J, et al.
Scand J Immunol
. 2002 Jul;
56(2):161-7.
PMID: 12121435
Increasing levels of proinflammatory cells, including eosinophils and basophils, are seen at the site of allergen challenge in allergic disease of the airways. Mechanisms for the recruitment of these cell...
12.
Denburg J, Sehmi R, Upham J
Int Arch Allergy Immunol
. 2001 Apr;
124(1-3):246-8.
PMID: 11306982
We and others have shown that IL-5 plays a central role in eosinophil and basophil differentiation, exerting its effects through the IL-5 receptor (IL-5R). Little is currently known concerning regulation...
13.
Gauvreau G, Wood L, Sehmi R, Watson R, Dorman S, Schleimer R, et al.
Am J Respir Crit Care Med
. 2000 Dec;
162(6):2139-44.
PMID: 11112128
Allergen inhalation by dual responder subjects with atopic asthma is associated with an increase in circulating eosinophil/basophil colony-forming units (Eo/B CFU) and granulocyte-macrophage colony- stimulating factor (GM-CSF) immunolocalization in Eo/B...
14.
Denburg J, Sehmi R, Saito H, Inman M, OByrne P
J Allergy Clin Immunol
. 2000 Nov;
106(5 Suppl):S242-6.
PMID: 11080738
In patients with allergic diseases, allergen provocation can activate a systemic response that provokes inflammatory cell production by the bone marrow. After release and differentiation of progenitor cells, eosinophils, basophils,...
15.
Lundahl J, Sehmi R, Hayes L, Howie K, Denburg J
Allergy
. 2000 Sep;
55(9):865-72.
PMID: 11003451
Background: The sequence of adhesion-molecule expression during eosinophil differentiation remains unclear. Methods: We analyzed the surface expression of alpha4, beta1, and beta7 integrins and compared it to established myeloid developmental...
16.
17.
Upham J, Hayes L, Lundahl J, Sehmi R, Denburg J
J Allergy Clin Immunol
. 1999 Aug;
104(2 Pt 1):370-5.
PMID: 10452759
Background: Recent findings point to an association between allergic asthma in adults and increased responsiveness of myeloid progenitor cells to certain hemopoietic growth factors. However, it is not clear at...
18.
Wood L, Sehmi R, Gauvreau G, Watson R, Foley R, Denburg J, et al.
Am J Respir Crit Care Med
. 1999 May;
159(5 Pt 1):1457-63.
PMID: 10228111
We have previously shown that allergen inhalation by asthmatics is associated with increases in bone marrow eosinophil/basophil colony-forming cells (Eo/B-CFU), and increases in CD34(+) hemopoietic progenitors expressing the alpha-subunit of...
19.
Denburg J, Sehmi R, Upham J, Wood L, Gauvreau G, OByrne P
Int Arch Allergy Immunol
. 1999 May;
118(2-4):101-3.
PMID: 10224351
Background: Following consistent demonstrations of the clinical relevance of fluctuations in eosinophil-basophil (Eo-B) progenitors in the blood of patients with a variety of allergic airway disorders, we have turned our...
20.
Denburg J, Inman M, Sehmi R, Uno M, OByrne P
Int Arch Allergy Immunol
. 1998 Dec;
117(3):155-9.
PMID: 9831802
The bone marrow actively participates in the production of IgER-positive inflammatory cells (eosinophils, basophils and mast cells), which are typically recruited to tissues in atopic individuals. Understanding the signalling between...