R S Arnold
Overview
Explore the profile of R S Arnold including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
869
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0
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Recent Articles
1.
Frohlich D, McCabe M, Arnold R, Day M
Oncogene
. 2008 Apr;
27(31):4353-62.
PMID: 18372916
The impact of oxidative stress in human cancer has been extensively studied. It is accepted that elevated reactive oxygen species (ROS) promote mutagenic DNA damage. Even with an extensive armament...
2.
Arnold R, Shi J, Murad E, Whalen A, Sun C, Polavarapu R, et al.
Proc Natl Acad Sci U S A
. 2001 May;
98(10):5550-5.
PMID: 11331784
Nox1, a homologue of gp91phox, the catalytic moiety of the superoxide (O(2)(-))-generating NADPH oxidase of phagocytes, causes increased O(2)(-) generation, increased mitotic rate, cell transformation, and tumorigenicity when expressed in...
3.
Lambeth J, Cheng G, Arnold R, Edens W
Trends Biochem Sci
. 2000 Oct;
25(10):459-61.
PMID: 11050424
No abstract available.
4.
Kuai J, Boman A, Arnold R, Zhu X, Kahn R
J Biol Chem
. 2000 Feb;
275(6):4022-32.
PMID: 10660559
Nine mutations in the switch I and switch II regions of human ADP-ribosylation factor 3 (ARF3) were isolated from loss-of-interaction screens, using two-hybrid assays with three different effectors. We then...
5.
Suh Y, Arnold R, Lassegue B, Shi J, Xu X, Sorescu D, et al.
Nature
. 1999 Sep;
401(6748):79-82.
PMID: 10485709
Reactive oxygen species (ROS) generated in some non-phagocytic cells are implicated in mitogenic signalling and cancer. Many cancer cells show increased production of ROS, and normal cells exposed to hydrogen...
6.
Kim J, Kim Y, Lee S, Lopez I, Arnold R, Lambeth J, et al.
FEBS Lett
. 1999 Jul;
454(1-2):42-6.
PMID: 10413092
Although oleate has been implicated in the regulation of phospholipase D (PLD) activity, the molecular identity of the oleate-stimulated PLD is still poorly understood. We now report that oleate selectively...
7.
Lopez I, Arnold R, Lambeth J
J Biol Chem
. 1998 May;
273(21):12846-52.
PMID: 9582313
Phospholipase D (PLD) has been implicated in a variety of cellular processes including vesicular transport, the respiratory burst, and mitogenesis. PLD1, first cloned from human, is activated by small GTPases...
8.
Arnold R, DePaoli-Roach A, Cornell R
Biochemistry
. 1997 May;
36(20):6149-56.
PMID: 9166786
The regulation of membrane binding and activity of purified CDP:phosphocholine cytidylyl-transferase (CT) by lipid activators and enzyme dephosphorylation was examined. The binding of CT to membranes was analyzed using sucrose-loaded...
9.
Arnold R, Newton A
J Cell Biochem
. 1996 Sep;
62(4):516-28.
PMID: 8891897
The lipid second messenger, phosphatidic acid, inhibits the intrinsic tyrosine kinase activity of the insulin receptor in detergent-lipid mixed micelles or in reconstituted membranes. Enzymatic studies revealed that this lipid...
10.
Arnold R, Cornell R
Biochemistry
. 1996 Jul;
35(30):9917-24.
PMID: 8703966
The contributions of electrostatic and hydrophobic interactions in the activation of cytidylyl-transferase (CT) by various negatively charged lipids were analyzed using small unilamellar or multilamellar vesicles (SUVs or MLVs). The...