R R Almon
Overview
Explore the profile of R R Almon including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
442
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Recent Articles
1.
Yang E, Almon R, Dubois D, Jusko W, Androulakis I
J Pharmacol Exp Ther
. 2007 Dec;
324(3):1243-54.
PMID: 18086872
One of the challenges in constructing biological models involves resolving meaningful data patterns from which the mathematical models will be generated. For models that describe the change of mRNA in...
2.
Androulakis I, Yang E, Almon R
Annu Rev Biomed Eng
. 2007 Mar;
9:205-28.
PMID: 17341157
Monitoring the change in expression patterns over time provides the distinct possibility of unraveling the mechanistic drivers characterizing cellular responses. Gene arrays measuring the level of mRNA expression of thousands...
3.
Sun Y, Dubois D, Almon R, Pyszczynski N, Jusko W
J Pharmacokinet Biopharm
. 1999 Sep;
26(6):619-48.
PMID: 10485078
Dose-dependent and repeated-dose effects of methylprednisolone (MPL) on down-regulation of glucocorticoid receptor messenger RNA (GR mRNA) and GR density, as well as tyrosine aminotransferase (TAT) mRNA and TAT induction by...
4.
Sagawa K, Han B, Dubois D, Murer H, Almon R, Morris M
J Pharmacol Exp Ther
. 1999 Aug;
290(3):1182-7.
PMID: 10454493
The effects of growth hormone (GH) treatment on renal sodium sulfate cotransport (NaSi-1) were studied in adult (9-10 months) and old (22-23 months) male Fischer 344 rats. All animals received...
5.
Han B, Dubois D, Boje K, Free S, Almon R
Nitric Oxide
. 1999 Aug;
3(4):281-91.
PMID: 10444367
Inducible nitric oxide synthase (iNOS) is a member of a family of primary inflammatory response genes. Quantitative measurement of iNOS mRNA levels is important for the study of gene expression...
6.
Sun Y, Lee H, Almon R, Jusko W
J Pharmacol Exp Ther
. 1999 May;
289(3):1523-32.
PMID: 10336548
The pharmacokinetics of recombinant human growth hormone (rhGH) and its effects on the induction of insulin-like growth factor I (IGF-I) were studied in juvenile rhesus monkeys. Disposition profiles of rhGH...
7.
Sun Y, Dubois D, Almon R, Jusko W
J Pharmacokinet Biopharm
. 1999 Mar;
26(3):289-317.
PMID: 10098101
A fourth-generation pharmacokinetic/pharmacodynamic (PK/PD) model for receptor/genemediated effects of corticosteroids was developed. Male adrenalectomized Wistar rats received a 50 mg/kg i.v. bolus dose of methylprednisolone (MPL). Plasma concentrations of MPL,...
8.
Sun Y, McKay L, Dubois D, Jusko W, Almon R
J Pharmacol Exp Ther
. 1999 Jan;
288(2):720-8.
PMID: 9918581
Muscle wasting and excessive fat deposition are side effects attendant to chronic corticosteroid treatment. Corticosteroid immunosuppression is necessary in circumstances such as transplantation. Pharmacokinetic/pharmacodynamic (PK/PD) modeling was used to help...
9.
Sagawa K, Dubois D, Almon R, Murer H, Morris M
J Pharmacol Exp Ther
. 1998 Dec;
287(3):1056-62.
PMID: 9864292
The renal transport and fractional reabsorption of inorganic sulfate is altered under conditions of sulfate deficiency or excess. The objective of this study was to examine the cellular mechanisms of...
10.
Sagawa K, Dubois D, Han B, Almon R, Biber J, Murer H, et al.
Pflugers Arch
. 1998 Nov;
437(1):123-9.
PMID: 9817796
The sodium-dependent sulfate transporter (NaSi-1) DNA has been recently identified from rat kidney cortex. The objective of this study was to develop a quantitative assay for the NaSi-1 transporter protein....