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R P Carty

Explore the profile of R P Carty including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 167
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Recent Articles
1.
Pincus M, Brandt-Rauf P, Michl J, Carty R, Friedman F
Cancer Invest . 2000 Mar; 18(1):39-50. PMID: 10701366
No abstract available.
2.
Pincus M, Carty R, Miller J
J Protein Chem . 1994 Oct; 13(7):629-33. PMID: 7702744
No abstract available.
3.
Singer P, Smalds A, Carty R, Mangel W, Sweet R
Science . 1993 Jul; 261(5121):621-2. PMID: 17758171
No abstract available.
4.
Singer P, Smalas A, Carty R, Mangel W, Sweet R
Science . 1993 Jan; 259(5095):669-73. PMID: 8430314
Crystals of bovine trypsin were acylated at the reactive residue, serine 195, to form the transiently stable p-guanidinobenzoate. Hydrolysis of this species was triggered in the crystals by a jump...
5.
Pincus M, Dykes D, Carty R, Miller J
Biochim Biophys Acta . 1991 Sep; 1097(2):133-9. PMID: 1911886
Platelet-type von Willebrand disease (PT-vWD) is an autosomal dominant bleeding disorder in which patient platelets exhibit an abnormally increased binding of circulating von Willebrand factor (vWF). We have recently shown...
6.
Pincus M, Hummel C, Brandt-Rauf P, Carty R
Int J Pept Protein Res . 1990 Jul; 36(1):56-66. PMID: 2401600
The binding and alkylation rate constants for the reaction of four bromoacetamido pyrimidine nucleosides and bromoacetamide with bovine pancreatic ribonuclease A (RNase A) have been determined as a function of...
7.
Brandt-Rauf P, Carty R, Chen J, Lee G, Rackovsky S, Pincus M
J Protein Chem . 1990 Apr; 9(2):137-42. PMID: 2201311
The carboxyl-terminal region of the ras oncogene-encoded p21 protein is critical to the protein's function, since membrane binding through the C-terminus is necessary for its cellular activity. X-ray crystal structures...
8.
Shah D, Chen J, Carty R, Pincus M, Scheraga H
Int J Pept Protein Res . 1989 Oct; 34(4):325-32. PMID: 2599773
Conformational analysis, based on ECEPP (Empirical Conformational Energy Program for Peptides) using the chain build-up procedure, was applied to determine the low-energy conformations for a series of tetrapeptides. The tetrapeptides...
9.
Brandt-Rauf P, Lee G, Carty R, Pincus M, Chen J
J Protein Chem . 1989 Aug; 8(4):563-73. PMID: 2572237
The P-glycoprotein of the mdr 1 gene is responsible for the phenomenon of multidrug resistance in human cells. The presumed drug-binding site of the wild-type P-glycoprotein contains a glycine at...
10.
Chen J, Lee G, Murphy R, Carty R, Brandt-Rauf P, Friedman E, et al.
J Biomol Struct Dyn . 1989 Apr; 6(5):859-75. PMID: 2686707
The GTP-binding p21 protein encoded by the ras-oncogene can be activated to cause malignant transformation of cells by substitution of a single amino acid at critical positions along the polypeptide...