R M Steinman
Overview
Explore the profile of R M Steinman including associated specialties, affiliations and a list of published articles.
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308
Citations
25478
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Recent Articles
21.
Granelli-Piperno A, Zhong L, Haslett P, Jacobson J, Steinman R
J Immunol
. 2000 Nov;
165(11):6620-6.
PMID: 11086107
Nonreplicating vectors are being considered in HIV-1 vaccine design. However, nonreplicating viruses are typically weak immunogens, leading to efforts to target the vaccine to mature dendritic cells (DCs). We have...
22.
Ignatius R, Mahnke K, Rivera M, Hong K, Isdell F, Steinman R, et al.
Blood
. 2000 Nov;
96(10):3505-13.
PMID: 11071648
Liposomes have been proposed as a vehicle to deliver proteins to antigen-presenting cells (APC), such as dendritic cells (DC), to stimulate strong T cell-mediated immune responses. Unfortunately, because of their...
23.
Ignatius R, Marovich M, Mehlhop E, Villamide L, Mahnke K, Cox W, et al.
J Virol
. 2000 Nov;
74(23):11329-38.
PMID: 11070033
Recombinant avipox viruses are being widely evaluated as vaccines. To address how these viruses, which replicate poorly in mammalian cells, might be immunogenic, we studied how canarypox virus (ALVAC) interacts...
24.
Mahnke K, Guo M, Lee S, Sepulveda H, Swain S, Nussenzweig M, et al.
J Cell Biol
. 2000 Nov;
151(3):673-84.
PMID: 11062267
Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC-205 multilectin receptor targets late endosomes or lysosomes rich...
25.
Guo M, Gong S, Maric S, Misulovin Z, Pack M, Mahnke K, et al.
Hum Immunol
. 2000 Sep;
61(8):729-38.
PMID: 10980384
DEC-205 is a multilectin receptor for adsorptive endocytosis, expressed in mouse dendritic cells (DC) and some epithelia. DEC-205 is homologous to the macrophage mannose receptor (MMR). A cDNA for murine...
26.
Ignatius R, Wei Y, Beaulieu S, Gettie A, Steinman R, Pope M, et al.
AIDS Res Hum Retroviruses
. 2000 Aug;
16(11):1055-9.
PMID: 10933620
Dendritic cells (DCs) have been shown to be important in the replication of human and simian immunodeficiency viruses (HIV and SIV, respectively) in vivo and in vitro. DCs express CD4...
27.
Steinman R, Pizlo Z, Pizlo F
Vision Res
. 2000 Aug;
40(17):2257-64.
PMID: 10927113
Max Wertheimer (1880-1943), the founder of the Gestalt School of Psychology, published a monograph on the perception of apparent motion in 1912, which initiated a new direction for a great...
28.
Malinov I, Epelboim J, Herst A, Steinman R
Vision Res
. 2000 Jul;
40(16):2083-90.
PMID: 10878269
We determined how saccades were used in the experiments described in Epelboim, Steinman, Kowler, Edwards, Pizlo, Erkelens and Collewijn (1995) [Vision Research, 35, 3401-3422], where unrestrained subjects looked at or...
29.
Munz C, Bickham K, Subklewe M, Tsang M, Chahroudi A, Kurilla M, et al.
J Exp Med
. 2000 May;
191(10):1649-60.
PMID: 10811859
The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV-induced tumors express this foreign antigen....
30.
Turley S, Inaba K, GARRETT W, Ebersold M, Unternaehrer J, Steinman R, et al.
Science
. 2000 Apr;
288(5465):522-7.
PMID: 10775112
Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands. Immature dendritic cells (DCs) sequester intact antigens in lysosomes,...