R L Idzerda
Overview
Explore the profile of R L Idzerda including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1643
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Recent Articles
1.
Belyamani M, Gangolli E, Idzerda R
Mol Cell Biol
. 2001 May;
21(12):3959-63.
PMID: 11359903
The protein kinase inhibitor (PKI) family includes three genes encoding small, heat-stable inhibitors of the cyclic AMP-dependent kinase PKA. Each PKI isoform contains a PKA inhibitory domain and a nuclear...
2.
Gangolli E, Belyamani M, Muchinsky S, Narula A, Burton K, McKnight G, et al.
Mol Cell Biol
. 2000 Apr;
20(10):3442-8.
PMID: 10779334
Protein kinase inhibitor (PKI) is a potent endogenous inhibitor of the cyclic AMP (cAMP)-dependent protein kinase (PKA). It functions by binding the free catalytic (C) subunit with a high affinity...
3.
Planas J, Cummings D, Idzerda R, McKnight G
J Biol Chem
. 1999 Dec;
274(51):36281-7.
PMID: 10593917
Targeted disruption of the RIIbeta subunit of protein kinase A (PKA) produces lean mice that resist diet-induced obesity. In this report we examine the effects of the RIIbeta knockout on...
4.
Wiley J, Wailes L, Idzerda R, McKnight G
J Biol Chem
. 1999 Feb;
274(10):6381-7.
PMID: 10037729
Regulation of protein kinase A by subcellular localization may be critical to target catalytic subunits to specific substrates. We employed epitope-tagged catalytic subunit to correlate subcellular localization and gene-inducing activity...
5.
McKnight G, Cummings D, Amieux P, Sikorski M, Brandon E, Planas J, et al.
Recent Prog Horm Res
. 1998 Oct;
53:139-59; discussion 160-1.
PMID: 9769707
The major regulator of lipolysis in white adipocytes and brown adipocytes is cAMP and the actions of cAMP are mediated by protein kinase A (PKA). Multiple subunits of PKA, including...
6.
Brandon E, Logue S, Adams M, Qi M, Sullivan S, Matsumoto A, et al.
J Neurosci
. 1998 Jun;
18(10):3639-49.
PMID: 9570795
Motor behavior is modulated by dopamine-responsive neurons in the striatum, where dopaminergic signaling uses G-protein-coupled pathways, including those that result in the activation of cAMP-dependent protein kinase (PKA). The RIIbeta...
7.
Hensch T, Gordon J, Brandon E, McKnight G, Idzerda R, Stryker M
J Neurosci
. 1998 Apr;
18(6):2108-17.
PMID: 9482797
Developing sensory systems are sculpted by an activity-dependent strengthening and weakening of connections. Long-term potentiation (LTP) and depression (LTD) in vitro have been proposed to model this experience-dependent circuit refinement....
8.
Hamilton S, Loose M, Qi M, Levey A, Hille B, McKnight G, et al.
Proc Natl Acad Sci U S A
. 1997 Dec;
94(24):13311-6.
PMID: 9371842
Muscarinic acetylcholine receptors are members of the G protein-coupled receptor superfamily expressed in neurons, cardiomyocytes, smooth muscle, and a variety of epithelia. Five subtypes of muscarinic acetylcholine receptors have been...
9.
Adams M, Brandon E, Chartoff E, Idzerda R, Dorsa D, McKnight G
Proc Natl Acad Sci U S A
. 1997 Oct;
94(22):12157-61.
PMID: 9342379
The antipsychotic drug, haloperidol, elicits the expression of neurotensin and c-fos mRNA in the dorsal lateral region of the striatum and produces an acute cataleptic response in rodents that correlates...
10.
Burton K, Johnson B, Hausken Z, Westenbroek R, Idzerda R, Scheuer T, et al.
Proc Natl Acad Sci U S A
. 1997 Oct;
94(20):11067-72.
PMID: 9380760
Preferential phosphorylation of specific proteins by cAMP-dependent protein kinase (PKA) may be mediated in part by the anchoring of PKA to a family of A-kinase anchor proteins (AKAPs) positioned in...