R L Felsted
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Explore the profile of R L Felsted including associated specialties, affiliations and a list of published articles.
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60
Citations
773
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Recent Articles
1.
Glover C, Hartman K, Felsted R
J Biol Chem
. 1997 Nov;
272(45):28680-9.
PMID: 9353336
N-Myristoyltransferase (NMT) catalyzes the cotranslational acylation with myristic acid of the NH2-terminal glycines of a number of cellular and viral proteins. Most of the in vitro NMT activity (60-85%) in...
2.
Turpin J, Terpening S, Schaeffer C, Yu G, Glover C, Felsted R, et al.
J Virol
. 1996 Sep;
70(9):6180-9.
PMID: 8709244
The Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys zinc fingers of retroviral nucleocapsid proteins are prime antiviral targets because of conservation of the Cys and His chelating residues and the absolute requirement of these fingers in...
3.
Felsted R, Glover C, Hartman K
J Natl Cancer Inst
. 1995 Nov;
87(21):1571-3.
PMID: 7563194
No abstract available.
4.
Glover C, Felsted R
J Biol Chem
. 1995 Sep;
270(39):23226-33.
PMID: 7559471
N-Myristoyltransferase (NMT) catalyzes the co-translational addition of myristic acid to the N-terminal glycine of many cellular, viral, and fungal proteins which are essential to normal cell functioning and/or are potential...
5.
Yu G, Shen F, Sturch S, Aquino A, Glazer R, Felsted R
J Biol Chem
. 1995 Mar;
270(9):4792-6.
PMID: 7876252
The human immunodeficiency virus type 1 internal structural protein precursor, p55, and its corresponding matrix proteolytic fragment, p17, are phosphorylated at Ser111 by protein kinase C. COS-7 cells transfected with...
6.
Burnette B, Yu G, Felsted R
J Biol Chem
. 1993 Apr;
268(12):8698-703.
PMID: 8473314
We have demonstrated that the 17-kDa N-terminal matrix protein (p17gag) of HIV-1 Pr55gag is a substrate for protein kinase C (PKC). Phosphorylation of p17gag and Pr55gag was studied in vivo...
7.
Burnette B, Kahn R, Glover C, Felsted R
Protein Expr Purif
. 1992 Oct;
3(5):395-402.
PMID: 1458053
The coding region of the N-terminal 17-kDa portion of HIV-1 Pr55gag (p17gag) was cloned into the pET-3c expression vector and was used to overexpress HIV-1 p17gag in Escherichia coli. Induction...
8.
Yu G, Felsted R
Virology
. 1992 Mar;
187(1):46-55.
PMID: 1736544
The effect of myristoylation on p27nef subcellular distribution and suppression of HIV-1 transcription was examined by transfecting COS-7 cells with plasmids expressing either myristoylated (pSVnef) or nonmyristolyated p27nef (pSVnefala2). Similar...
9.
Glover C, Tellez M, Guziec Jr F, Felsted R
Biochem Pharmacol
. 1991 Mar;
41(6-7):1067-74.
PMID: 2009075
Several substrate and product analogs were synthesized and tested as in vitro inhibitors of bovine brain N-myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97). At 40 microM, the acyl CoA analog, S-(2-ketopentadecyl)-CoA, completely...
10.
Politi P, Arnold S, Felsted R, Sinha B
Mol Pharmacol
. 1990 Jun;
37(6):790-6.
PMID: 1972771
The interaction of etoposide (VP-16), Vinca alkaloids, and verapamil with the P-glycoprotein (P-gp) was studied in human breast (MCF-7) and Chinese hamster lung (DC3F) cell lines and the corresponding multidrug-resistant...