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R L Dubowy

Explore the profile of R L Dubowy including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 63
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Recent Articles
1.
Souid A, Fahey R, Aktas M, Sayin O, Karjoo S, Newton G, et al.
Drug Metab Dispos . 2001 Oct; 29(11):1460-6. PMID: 11602522
The Pediatric Oncology Group study for metastatic Ewing's sarcoma used amifostine and mesna with the alkylating agents. To determine the fate of combined drug thiols, we measured thiol levels in...
2.
Korones D, Fisher P, Cohen K, Dubowy R
Med Pediatr Oncol . 2000 Jul; 35(1):80-2. PMID: 10881014
No abstract available.
3.
Souid A, Fahey R, Dubowy R, Newton G, Bernstein M
Cancer Chemother Pharmacol . 1999 Nov; 44(6):498-504. PMID: 10550571
Purpose: Previous WR-2721 human pharmacokinetic studies were limited to plasma levels in patients receiving platinum-based compounds, and none includes the effects of WR-2721 on endogenous thiols. In the present study...
4.
Weitman S, Langevin A, Berkow R, Thomas P, Hurwitz C, Kraft A, et al.
Clin Cancer Res . 1999 Sep; 5(9):2344-8. PMID: 10499603
Bryostatin-1, a macrocyclic lactone, appears to elicit a wide range of biological responses including modulation of protein kinase C (PKC). PKC, one of the major elements in the signal transduction...
5.
Souid A, Newton G, Dubowy R, Fahey R, Bernstein M
Cancer Chemother Pharmacol . 1998 Oct; 42(5):400-6. PMID: 9771955
Purpose: WR-2721 [S-2-(3-aminopropylamino)ethylphosphorothioic acid] is a chemoprotective agent that is currently in pediatric clinical trials. It is a prodrug that is dephosphorylated by alkaline phosphatase to the active free thiol...
6.
Poe L, Dubowy R, Hochhauser L, Collins G, Crosley C, Kanzer M, et al.
AJNR Am J Neuroradiol . 1994 Nov; 15(10):1921-8. PMID: 7863943
Purpose: To describe the involvement of the cerebellum by a gliotic and demyelinating process in Langerhans cell histiocytosis. Methods: A retrospective analysis of all (N = 30) cases of Langerhans...
7.
Graham M, Yeager A, Leventhal B, Wiley J, Civin C, Strauss L, et al.
J Clin Oncol . 1992 Dec; 10(12):1857-64. PMID: 1453200
Purpose: The purpose of this study was to determine the toxicities of and responses to high-dose busulfan and cyclophosphamide with autologous bone marrow transplant (ABMT) in patients with recurrent or...
8.
Kurec A, Belair P, Stefanu C, Barrett D, Dubowy R, Davey F
Cancer . 1991 Jun; 67(12):3081-6. PMID: 2044051
Leukemic cells from 51 pediatric patients (younger than 18 years) diagnosed with acute lymphoid leukemia by standard morphologic and cytochemical methods were subjected to flow cytometric studies using a panel...
9.
Sadowitz P, Dubowy R
Am J Pediatr Hematol Oncol . 1990 Jan; 12(2):198-200. PMID: 2378414
Aplastic anemia is characterized by reduced production of mature erythrocytes, granulocytes, and platelets from marrow stem cells leading to peripheral blood pancytopenia. In many cases, it appears that there is...
10.
Hutchinson R, Kurec A, Dubowy R, Davey F
Am J Clin Pathol . 1987 Jul; 88(1):83-6. PMID: 2440297
The expression of the T6 antigen on malignant lymphoid cells has been considered strong evidence in support of T-cell lineage and thymic stage of differentiation of the neoplastic cells. Thus,...