R Jeroen Pasterkamp
Overview
Explore the profile of R Jeroen Pasterkamp including associated specialties, affiliations and a list of published articles.
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Articles
162
Citations
7529
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Recent Articles
11.
Vieira de Sa R, Sudria-Lopez E, Canizares Luna M, Harschnitz O, van den Heuvel D, Kling S, et al.
Nat Commun
. 2024 Aug;
15(1):7484.
PMID: 39209824
Intermediate-length repeat expansions in ATAXIN-2 (ATXN2) are the strongest genetic risk factor for amyotrophic lateral sclerosis (ALS). At the molecular level, ATXN2 intermediate expansions enhance TDP-43 toxicity and pathology. However,...
12.
Rybiczka-Tesulov M, Garritsen O, Veno M, Wieg L, Dijk R, Rahimi K, et al.
Nat Commun
. 2024 Aug;
15(1):6773.
PMID: 39117691
Midbrain dopamine (mDA) neurons play an essential role in cognitive and motor behaviours and are linked to different brain disorders. However, the molecular mechanisms underlying their development, and in particular...
13.
Abdelaal T, Grossouw L, Pasterkamp R, Lelieveldt B, Reinders M, Mahfouz A
NAR Genom Bioinform
. 2024 Aug;
6(3):lqae100.
PMID: 39108639
RNA Velocity allows the inference of cellular differentiation trajectories from single-cell RNA sequencing (scRNA-seq) data. It would be highly interesting to study these differentiation dynamics in the spatial context of...
14.
Caldi Gomes L, Hanzelmann S, Hausmann F, Khatri R, Oller S, Parvaz M, et al.
Nat Commun
. 2024 Jun;
15(1):4893.
PMID: 38849340
Amyotrophic lateral sclerosis (ALS) is a debilitating motor neuron disease and lacks effective disease-modifying treatments. This study utilizes a comprehensive multiomic approach to investigate the early and sex-specific molecular mechanisms...
15.
Prince N, Peralta Marzal L, Markidi A, Ahmed S, Adolfs Y, Pasterkamp R, et al.
Acta Pharmacol Sin
. 2024 Apr;
45(8):1591-1603.
PMID: 38589690
Autism spectrum disorder (ASD) is a cluster of neurodevelopmental disorders characterized by deficits in communication and behavior. Increasing evidence suggests that the microbiota-gut-brain axis and the likely related immune imbalance...
16.
Verkerke M, Berdenis van Berlekom A, Donega V, Vonk D, Sluijs J, Butt N, et al.
Glia
. 2023 Oct;
72(2):362-374.
PMID: 37846809
Cerebral organoids (CerOrgs) derived from human induced pluripotent stem cells (iPSCs) are a valuable tool to study human astrocytes and their interaction with neurons and microglia. The timeline of astrocyte...
17.
Blot F, White J, van Hattem A, Scotti L, Balaji V, Adolfs Y, et al.
Nat Commun
. 2023 Sep;
14(1):5375.
PMID: 37666824
No abstract available.
18.
Harwood A, Petrakis S, Oktay Y, Pasterkamp R
Front Cell Dev Biol
. 2023 Aug;
11:1244425.
PMID: 37560163
No abstract available.
19.
Blot F, White J, van Hattem A, Scotti L, Balaji V, Adolfs Y, et al.
Nat Commun
. 2023 Jul;
14(1):4358.
PMID: 37468512
The classification of neuronal subpopulations has significantly advanced, yet its relevance for behavior remains unclear. The highly organized flocculus of the cerebellum, known to fine-tune multi-axial eye movements, is an...
20.
Bassil K, Krontira A, Leroy T, Escoto A, Snijders C, Pernia C, et al.
Neurobiol Stress
. 2023 Mar;
23:100530.
PMID: 36891528
Hypothalamic-pituitary adrenal (HPA)axis dysregulation has long been implicated in stress-related disorders such as major depression and post-traumatic stress disorder. Glucocorticoids (GCs) are released from the adrenal glands as a result...