R J Vandenberg
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Explore the profile of R J Vandenberg including associated specialties, affiliations and a list of published articles.
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24
Citations
680
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Recent Articles
1.
Alexander S, Benson H, Faccenda E, Pawson A, Sharman J, McGrath J, et al.
Br J Pharmacol
. 2014 Feb;
170(8):1449-58.
PMID: 24528237
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of...
2.
Carland J, Mansfield R, Ryan R, Vandenberg R
Br J Pharmacol
. 2012 Sep;
168(4):891-902.
PMID: 22978602
Background And Purpose: Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2. Selective inhibitors of GlyT1 have been developed for the...
3.
Vandenberg R
Handb Exp Pharmacol
. 2006 May;
(175):113-35.
PMID: 16722233
Glutamate transporters are a family of transporters that regulate extracellular glutamate concentrations so as to maintain a dynamic and high-fidelity cell signalling process in the brain. Site-directed mutagenesis has been...
4.
Aubrey K, Vandenberg R
Br J Pharmacol
. 2001 Nov;
134(7):1429-36.
PMID: 11724748
1. The regulation of glycine concentrations within excitatory synapses is poorly understood and it has been proposed that the GLYT1 subtypes of glycine transporters play a critical role in determining...
5.
Poulsen M, Vandenberg R
J Physiol
. 2001 Jul;
534(Pt 1):159-67.
PMID: 11432999
1. The effects of niflumic acid on the substrate-gated currents mediated by the glutamate transporter EAAT4 expressed in Xenopus laevis oocytes were examined using radiolabelled substrate flux measurements and two-electrode...
6.
Mitrovic A, Plesko F, Vandenberg R
J Biol Chem
. 2001 May;
276(28):26071-6.
PMID: 11352900
Glutamate transport by the excitatory amino acid transporters (EAATs) is coupled to the co-transport of 3 Na(+) ions and 1 H(+) and the counter-transport of 1 K(+) ion, which ensures...
7.
Dutton J, Poronnik P, Li G, Holding C, Worthington R, Vandenberg R, et al.
Neuropharmacology
. 2000 Aug;
39(11):2054-66.
PMID: 10963749
The P2X(1) purinergic receptor subtype occurs on smooth muscle cells of the vas deferens and urinary bladder where it is localized in two different size receptor clusters, with the larger...
8.
Aubrey K, Mitrovic A, Vandenberg R
Mol Pharmacol
. 2000 Jun;
58(1):129-35.
PMID: 10860934
In the central nervous system, glycine is a coagonist with glutamate at the N-methyl-D-aspartate subtype of ionotropic glutamate receptors. The GLYT1b subtype of glycine transporters is expressed in similar regions...
9.
Vandenberg R
Clin Exp Pharmacol Physiol
. 1998 Jul;
25(6):393-400.
PMID: 9673812
1. Glutamate is the predominant excitatory neurotransmitter in the brain, but it is also a potent neurotoxin. Following release of glutamate from presynaptic vesicles into the synapse and activation of...
10.
Vandenberg R, Mitrovic A, Johnston G
Mol Pharmacol
. 1998 Jul;
54(1):189-96.
PMID: 9658205
Zinc ions (Zn2+) are stored in synaptic vesicles with glutamate in a number of regions of the brain. When released into the synapse, Zn2+ modulates the activity of various receptors...