R J Cannell
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Explore the profile of R J Cannell including associated specialties, affiliations and a list of published articles.
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14
Citations
53
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Recent Articles
1.
Taylor M, Lamb D, Cannell R, Dawson M, Kelly S
Biochem Biophys Res Commun
. 2000 Dec;
279(2):708-11.
PMID: 11118349
Immobilisation of cells and enzymes can be a convenient and rapid way for testing and transforming substances. Cytochromes P450 may be useful in numerous biotransformations of varied lipophilic substrates, performing...
2.
Kennedy T, Webb G, Cannell R, Kinsman O, Middleton R, Sidebottom P, et al.
J Antibiot (Tokyo)
. 1999 Jan;
51(11):1012-8.
PMID: 9918394
The isolation and structure determination of 6 analogues of the fungal protein synthesis inhibitor GR135402, from Graphium putredinis, is described. The relative potencies of the compounds as protein synthesis inhibitors...
3.
Cannell R, Rashid T, Ismail I, Sidebottom P, Knaggs A, Marshall P
Xenobiotica
. 1997 Feb;
27(2):147-57.
PMID: 9058529
1. Biotransformation of warfarin by the fungus Beauveria bassiana (ATCC 7159) yielded the first reported phase II warfarin metabolite, 3'4'-dihydroxywarfarin-3'-[4-methoxyglucoside], another previously unreported metabolite, 3',4'-dihydroxywarfarin and also 4'-hydroxywarfarin. 2. Biotransformation...
4.
Cannell R, Knaggs A, Dawson M, Manchee G, Eddershaw P, WATERHOUSE I, et al.
Drug Metab Dispos
. 1995 Jul;
23(7):724-9.
PMID: 7587961
Screening a range of microorganisms incubated with the angiotensin II antagonist GR117289 resulted in the use of Streptomyces rimosus to generate five related biotransformation products. These comprised three compounds hydroxylated...
5.
Middleton R, Foster G, Cannell R, Sidebottom P, Taylor N, Noble D, et al.
J Antibiot (Tokyo)
. 1995 Apr;
48(4):311-6.
PMID: 7775268
Microorganisms were screened for the ability to modify the squalene synthase inhibitor squalestatin 1. Biotransformation of 1 by two actinomycetes, S15106 and S15138, yielded three products hydroxylated on the 4,6-dimethyl-oct-2-enoyl...
6.
Cannell R, Dawson M, Hale R, Hall R, Noble D, Lynn S, et al.
J Antibiot (Tokyo)
. 1994 Feb;
47(2):247-9.
PMID: 8150722
No abstract available.
7.
Cannell R, Dawson M, Hale R, Hall R, Noble D, Lynn S, et al.
J Antibiot (Tokyo)
. 1993 Sep;
46(9):1381-9.
PMID: 8226317
Feeding of fluorinated benzoic acids to fermentations of a Phoma sp. resulted in the biosynthesis of a series of novel fluorinated squalestatins. The feeding studies, isolation, structural elucidation and biological...
8.
Jones C, Sidebottom P, Cannell R, Noble D, Rudd B
J Antibiot (Tokyo)
. 1992 Sep;
45(9):1492-8.
PMID: 1429235
The biosynthetic origin of the carbon and oxygen atoms of the novel fungal secondary metabolite 1 was studied. Incorporation studies with single and multiple labelled 13C precursors indicated that the...
9.
Cannell R
Appl Biochem Biotechnol
. 1990 Oct;
26(1):85-105.
PMID: 2268145
The review gives a general outline of macro- and microalgal biotechnology. The main methods by which algae are cultivated and harvested are described. The first section deals with the environmental...
10.
Winder J, Cannell R, Walker J, Delbarre S, Francisco C, Farmer P
Biochem Soc Trans
. 1989 Dec;
17(6):1030-1.
PMID: 2516818
No abstract available.