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R Hoffman

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Articles 489
Citations 4153
Followers 0
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Recent Articles
1.
Irvin-Barnwell E, Benson K, Lu M, Ragin A, Wheeler J, Hoffman R
J Environ Anal Toxicol . 2021 Jun; 8(1). PMID: 34094707
In 2006, the Agency for Toxic Substances and Disease Registry received a request to determine whether a cluster of polycythemia vera patients existed in a northeast Pennsylvania community. A significant...
2.
Mascarenhas J, Marcellino B, Lu M, Kremyanskaya M, Fabris F, Sandy L, et al.
Leuk Res . 2019 Nov; 88:106272. PMID: 31778911
Ruxolitinib, a selective JAK1/JAK2 inhibitor, is the current first line therapy for myelofibrosis (MF), which reduces symptomatology and splenomegaly, but does not clearly modify disease course. Panobinostat, a histone deacetylase...
3.
Le Floch B, Bastiaens H, Le Reste J, Lingner H, Hoffman R, Czachowski S, et al.
BMC Fam Pract . 2019 Aug; 20(1):96. PMID: 31395016
Background: General Practice (GP) seems to be perceived as less attractive throughout Europe. Most of the policies on the subject focused on negative factors. An EGPRN research team from eight...
4.
Mascarenhas J, Kosiorek H, Prchal J, Yacoub A, Berenzon D, Baer M, et al.
Leukemia . 2019 Aug; 33(12):2974-2978. PMID: 31363161
No abstract available.
5.
Marcellino B, Hoffman R, Mascarenhas J
Leuk Res . 2018 Dec; 76:94-95. PMID: 30501902
No abstract available.
6.
Mahidhara R, Hoffman R, Simmons R, Billiar T
ScientificWorldJournal . 2018 Aug; 1:107. PMID: 30147588
No abstract available.
7.
Gowin K, Kosiorek H, Dueck A, Mascarenhas J, Hoffman R, Reeder C, et al.
Leuk Res . 2017 Jun; 60:31-35. PMID: 28646676
Myelofibrosis is a myeloproliferative neoplasm that is characterized by splenomegaly, profound symptom burden, and cytopenias. JAK inhibitor therapy offers improvements in splenomegaly, symptom burden, and potentially survival; however, cytopenias remain...
8.
Mosoyan G, Kraus T, Ye F, Eng K, Crispino J, Hoffman R, et al.
Leukemia . 2017 Mar; 31(11):2458-2467. PMID: 28270692
Imetelstat (GRN163L) is a specific telomerase inhibitor that has demonstrated clinical activity in patients with myeloproliferative neoplasms (MPN) and in patients with solid tumors. The antitumor effects were associated with...
9.
Hoffman R, Ranjbar G, Madden A
Eur J Clin Nutr . 2016 Mar; 70(9):1089-91. PMID: 27026422
This pilot study compared inhibition of the glycaemic response to glucose by a dietary source of quercetin glucosides (onion) in lactose-tolerant adults (n=12) and lactose-intolerant adults (n=12). We hypothesised that...
10.
Tamari R, Mughal T, Rondelli D, Hasserjian R, Gupta V, Odenike O, et al.
Bone Marrow Transplant . 2015 Feb; 50(5):628-36. PMID: 25665047
At present, allo-SCT is the only curative treatment for patients with myelofibrosis (MF). Unfortunately, a significant proportion of candidate patients are considered transplant ineligible due to their poor general condition...