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J E Straneva

Explore the profile of J E Straneva including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 64
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Recent Articles
1.
Straneva J, Van Besien K, Derigs G, Hoffman R
Exp Hematol . 1992 Jan; 20(1):47-50. PMID: 1577093
Interleukin 6 (IL-6) is a multifunctional cytokine that also influences megakaryocyte (MK) development. To delineate the relationship between IL-6 and thrombopoietin (TPO), the putative physiological regulator of MK maturation, serum...
2.
Antony A, Briddell R, Brandt J, Straneva J, Verma R, Miller M, et al.
J Clin Invest . 1991 Jan; 87(1):313-25. PMID: 1702099
We tested the hypothesis that anti-placental folate receptor (PFR) antiserum-mediated effects on hematopoietic progenitor cells in vitro of increased cell proliferation and megaloblastic morphology were independent responses. We determined that...
3.
Hoffman R, Briddell R, Straneva J, Brandt J, Bruno E, Ganser A, et al.
Prog Clin Biol Res . 1990 Jan; 338:75-103. PMID: 2189142
No abstract available.
4.
Straneva J, Briddell R, McDONALD T, Yang H, Hoffman R
Exp Hematol . 1989 Dec; 17(11):1122-7. PMID: 2684680
Aplastic anemia serum (AAS) contains humoral factors that alter both proliferation and maturation of human megakaryocytes (MK). The ability of AAS to augment MK colony formation (colony-forming unit, CFU-MK) was...
5.
Briddell R, Brandt J, Straneva J, Srour E, Hoffman R
Blood . 1989 Jul; 74(1):145-51. PMID: 2473794
Two classes of human marrow megakaryocyte progenitor cells are described. Colony-forming unit-megakaryocyte (CFU-MK)-derived colonies appeared in vitro after 12-day incubation; burst-forming unit-megakaryocyte (BFU-MK)-derived colonies appeared after 21 days. CFU-MK-derived colonies...
6.
Straneva J, Briddell R, Hui S, Hoffman R
Eur J Haematol . 1989 Mar; 42(3):293-7. PMID: 2784391
Human bone marrow was depleted of progenitors (CFU-MK), but enriched for recognizable megakaryocytes (MK), and placed in cultures with serum from either normal donors (NABS) or patients with primary (PTS)...
7.
Roth B, Sledge Jr G, Straneva J, Brandt J, Goheen M, Hoffman R
Blood . 1988 Jul; 72(1):202-7. PMID: 3134065
Megakaryocytes are relatively rare components of human bone marrow, making the study of their maturation difficult. Phorbol esters can act as differentiating agents in a number of cell systems including...
8.
Williams D, Bicknell D, Park L, Straneva J, Cooper S, Broxmeyer H
Proc Natl Acad Sci U S A . 1988 Jan; 85(2):487-91. PMID: 2829188
Purified recombinant murine granulocyte/macrophage colony-stimulating factor (GM-CSF) was labeled with 125I and used to examine the GM-CSF receptor on unfractionated normal murine bone marrow cells, casein-induced peritoneal exudate cells, and...
9.
Williams D, Straneva J, Cooper S, Shadduck R, Waheed A, Gillis S, et al.
Exp Hematol . 1987 Nov; 15(10):1007-12. PMID: 3311784
Purified preparations of natural CSF-1 (nCSF-1), recombinant GM-CSF (rGM-CSF), and recombinant IL-3 (rIL-3), alone and in combination, were investigated for their proliferative effects on highly enriched murine granulocyte-macrophage progenitor cells...
10.
Straneva J, Yang H, Hui S, Bruno E, Hoffman R
Exp Hematol . 1987 Jul; 15(6):657-63. PMID: 3595764
Suspensions of enriched human megakaryocytes (MK) devoid of MK progenitors (CFU-MK) undergo complete cytoplasmic maturation in vitro. MK were cultured in the presence of normal human AB serum (NABS) to...