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R H Swerdlow

Explore the profile of R H Swerdlow including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1634
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Recent Articles
1.
Guilford B, Ryals J, Lezi E, Swerdlow R, Wright D
J Neurol Neurosci . 2017 Aug; 8(2). PMID: 28775932
Background: Mitochondrial dysfunction is purported as a contributory mechanism underlying diabetic neuropathy, but a defined role for damaged mitochondria in diabetic nerves remains unclear, particularly in standard diabetes models. Experiments...
2.
Swerdlow R, Koppel S, Weidling I, Hayley C, Ji Y, Wilkins H
Prog Mol Biol Transl Sci . 2017 Mar; 146:259-302. PMID: 28253988
Mitochondrial and bioenergetic function change with advancing age and may drive aging phenotypes. Mitochondrial and bioenergetic changes are also documented in various age-related neurodegenerative diseases, including Alzheimer's disease (AD). In...
3.
Honea R, Swerdlow R, Vidoni E, Goodwin J, Burns J
Neurology . 2010 Jan; 74(2):113-20. PMID: 20065246
Objective: A consistently identified risk factor for Alzheimer disease (AD) is family history of dementia, with maternal transmission significantly more frequent than paternal transmission. A history of maternal AD may...
4.
Swerdlow R, Miller B, Lopes M, Mandell J, Wooten G, Damgaard P, et al.
Neurology . 2009 Jan; 72(3):260-7. PMID: 19153373
Objective: To describe a multigenerational kindred with a frontotemporal dementia clinical syndrome (FTDS), extensive subcortical gliosis pathology, and autosomal dominant genetics. Methods: Clinical, imaging, and pathologic evaluations of multiple family...
5.
Burns J, Cronk B, Anderson H, Donnelly J, Thomas G, Harsha A, et al.
Neurology . 2008 Jul; 71(3):210-6. PMID: 18625967
Objective: To examine the correlation of cardiorespiratory fitness with brain atrophy and cognition in early-stage Alzheimer disease (AD). Background: In normal aging physical fitness appears to mitigate functional and structural...
6.
Swerdlow R, Wooten G
Ann Neurol . 2001 Oct; 50(4):537-40. PMID: 11601506
Sex-linked male deafness and dystonia (Mohr-Tranebjaerg syndrome) arises from mutation of the deafness/dystonia peptide (DDP) gene. We describe a novel guanine deletion at nucleotide 108 of the DDP gene in...
7.
Swerdlow R, Parks J, PATTEE G, Parker Jr W
Amyotroph Lateral Scler Other Motor Neuron Disord . 2001 Jul; 1(3):185-90. PMID: 11464951
Neurodegeneration in amyotrophic lateral sclerosis (ALS) is characterized by the specific loss of central and peripheral motor neurons. While this pattern of neuronal demise gives rise to a distinct clinical...
8.
Currie L, Harrison M, Trugman J, Bennett J, Swerdlow R, Manning C, et al.
J Neurol Neurosurg Psychiatry . 2001 Jul; 71(1):130-1. PMID: 11439965
No abstract available.
9.
Cardoso S, Santos S, Swerdlow R, Oliveira C
FASEB J . 2001 Jun; 15(8):1439-41. PMID: 11387250
No abstract available.
10.
Swerdlow R, Parks J, Cassarino D, Binder D, Bennett Jr J, Di Iorio G, et al.
Exp Neurol . 2001 May; 169(2):479-85. PMID: 11358461
Complex I activity is reduced in cytoplasmic hybrid (cybrid) cell lines that contain mitochondrial DNA (mtDNA) from sporadic Parkinson's disease (PD) patients. This implies that mtDNA aberration occurs in sporadic...