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R G Mehta

Explore the profile of R G Mehta including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 77
Citations 1898
Followers 0
Related Specialties
Oncology
Biochemistry
Biology
Top 10 Co-Authors
R C Moon
J M Pezzuto
A D Kinghorn
R R Mehta
W L Cerny
R M Moriarty
D L McCormick
S K Lee
C F Thomas
M E HAWTHORNE
Published In
Cancer Res
Anticancer Res
J Natl Cancer Inst
Carcinogenesis
Eur J Cancer
Affiliations
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Recent Articles
1.
Actions of vitamin D are mediated by the TLR4 pathway in inflammation-induced colon cancer
Murillo G, Nagpal V, Tiwari N, Benya R, Mehta R
J Steroid Biochem Mol Biol . 2010 Mar; 121(1-2):403-7. PMID: 20214986
Many chronic inflammatory diseases are associated with increased risk of developing cancer. In the colon, strong support for a link between chronic inflammation and cancer extends, in part, from population-based...
2.
Resveratrol inhibits rhabdomyosarcoma cell proliferation
Chow A, Murillo G, Yu C, van Breemen R, Boddie A, Pezzuto J, et al.
Eur J Cancer Prev . 2005 Jul; 14(4):351-6. PMID: 16030425
Rhabdomysarcoma is the most common soft tissue tumour in children under the age of 15. Although the introduction of multimodal treatment programmes, including chemotherapy, radiation therapy and excision have increased...
3.
Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest
Murillo G, Salti G, Kosmeder 2nd J, Pezzuto J, Mehta R
Eur J Cancer . 2002 Dec; 38(18):2446-54. PMID: 12460790
As previously demonstrated, deguelin [(7aS, BaS)-13, 13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzo-pyrano[3,4-b:6',5'-e]pyran-7(7aH)-one mediates anti-proliferative properties in a variety of cell types. In the present study, deguelin was found to suppress the growth of HT-29 colon...
4.
Cruciferous vegetables and cancer prevention
Murillo G, Mehta R
Nutr Cancer . 2002 Jul; 41(1-2):17-28. PMID: 12094621
In recent years, cancer prevention by natural products has received considerable attention. The potential protective role of cruciferous vegetables and active components present in these vegetables, such as isothiocyanates and...
5.
Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures
Waffo-Teguo P, HAWTHORNE M, Cuendet M, Merillon J, Kinghorn A, Pezzuto J, et al.
Nutr Cancer . 2002 Apr; 40(2):173-9. PMID: 11962253
Moderate consumption of wine is associated with a reduced risk of cancer. Grape plant cell cultures were used to purify 12 phenols: the stilbenoids trans-astringin, trans-piceid (2), trans-resveratroloside, trans-resveratrol, trans-piceatannol,...
6.
In vitro transformation of human congenital naevus to malignant melanoma
Mehta R, Bratescu L, GRAVES J, Shilkaitis A, Green A, Mehta R, et al.
Melanoma Res . 2002 Feb; 12(1):27-33. PMID: 11828255
The incidence of melanoma is estimated to be growing at the second fastest rate among all cancers in the United States. The progression of the melanocyte to a malignant melanoma...
7.
Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture
Mata-Greenwood E, Daeuble J, Grieco P, Dou J, McChesney J, Mehta R, et al.
J Nat Prod . 2002 Jan; 64(12):1509-13. PMID: 11754601
In an effort to discover new chemotherapeutic/chemopreventive agents from natural sources, brusatol (1) was found to induce HL-60 cellular differentiation, accompanied by strong antiproliferative and cytotoxic effects. A series of...
8.
Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models
Bhat K, Lantvit D, Christov K, Mehta R, Moon R, Pezzuto J
Cancer Res . 2001 Oct; 61(20):7456-63. PMID: 11606380
Trans-3,4',5-trihydroxystilbene (resveratrol), a phytoalexin present in grapes and grape products such as wine, has been identified as a chemopreventive agent. Recent studies performed with MCF-7 human breast cancer cells have...
9.
Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity
Gu J, Park E, Luyengi L, HAWTHORNE M, Mehta R, Farnsworth N, et al.
Phytochemistry . 2001 Aug; 58(1):121-7. PMID: 11524121
A triterpenoid, 3beta-cis-p-coumaroyloxy-2alpha,23-dihydroxyolean-12-en-28-oic acid (1), and two natural products, 3beta-trans-p-coumaroyloxy-2alpha,23-dihydroxyolean-12-en-28-oic acid (2) and 23-trans-p-coumaroyloxy-2alpha,3beta-dihydroxyolean-12-en-28-oic acid (3), were isolated from a chloroform-soluble extract of the stems of Eugenia sandwicensis, along with...
10.
Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells
Mata-Greenwood E, Ito A, Westenburg H, Cui B, Mehta R, Kinghorn A, et al.
Anticancer Res . 2001 Aug; 21(3B):1763-70. PMID: 11497257
Non-physiological inducers of terminal differentiation have been used as novel therapies for the prevention and therapy of cancer. We have used cultured HL-60 promyelocytic cells to monitor differentiation, proliferation and...