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R R Mehta

Explore the profile of R R Mehta including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 297
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Recent Articles
1.
Mehta R, Bratescu L, GRAVES J, Shilkaitis A, Green A, Mehta R, et al.
Melanoma Res . 2002 Feb; 12(1):27-33. PMID: 11828255
The incidence of melanoma is estimated to be growing at the second fastest rate among all cancers in the United States. The progression of the melanocyte to a malignant melanoma...
2.
Mehta R, Bhat K, HAWTHORNE M, Kopelovich L, Mehta R, Christov K, et al.
J Natl Cancer Inst . 2001 Jul; 93(14):1103-6. PMID: 11459872
No abstract available.
3.
Shilkaitis A, Graves J, Mehta R, Hu L, You M, Lubet R, et al.
Cell Growth Differ . 2000 Aug; 11(8):437-45. PMID: 10965848
Previously, we found that vorozole (Vz), a nonsteroidal aromatase inhibitor, suppresses the development and progression of mammary tumors in rats. Here we evaluated for the first time the expression of...
4.
Salti G, Grewal S, Mehta R, Das Gupta T, Boddie Jr A, Constantinou A
Eur J Cancer . 2000 Apr; 36(6):796-802. PMID: 10762754
The present study was undertaken to determine if (a) genistein induces topo II-mediated DNA damage in HT-29 colon cancer cells; and (b) if this damage is required to induce apoptosis....
5.
Lazzaro G, Agadir A, Qing W, Poria M, Mehta R, Moriarty R, et al.
Eur J Cancer . 2000 Apr; 36(6):780-6. PMID: 10762752
The role of the active metabolite of vitamin D, 1,25 dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), in cell differentiation is well established. However, its use as a differentiating agent in a clinical setting...
6.
Mehta R, Bratescu L, GRAVES J, Green A, Mehta R
Int J Oncol . 1999 Dec; 16(1):65-73. PMID: 10601550
The active metabolite of vitamin D, 1alpha,25-dihydroxyvitamin D3, can induce differentiation in breast cancer cells; however, it is hypercalcemic in vivo. Therefore, development of non-calcemic analogs of vitamin D has...
7.
Lee S, Cui B, Mehta R, Kinghorn A, Pezzuto J
Chem Biol Interact . 1998 Dec; 115(3):215-28. PMID: 9851291
A total of five 1H-cyclopenta[b]benzofuran lignans (1-5) isolated from the stems of Aglaia elliptica B1. (Meliaceae) inhibited the growth of human cancer cells in culture. Of particular note, the IC50...
8.
Constantinou A, Krygier A, Mehta R
Am J Clin Nutr . 1998 Dec; 68(6 Suppl):1426S-1430S. PMID: 9848511
Results of recent studies in animal models of mammary carcinogenesis showed that the soybean isoflavone genistein is a chemopreventive agent. The objective of the present study was to determine whether...
9.
Mehta R, HAWTHORNE M, GRAVES J, Mehta R
Eur J Cancer . 1998 Nov; 34(6):902-7. PMID: 9797705
A clinical trial of N-[4-hydroxyphenyl]retinamide (4-HPR) has been in progress for the past 4 years to evaluate its role in chemoprevention of breast cancer. However, it is currently not known...
10.
Mehta R, McDermott J, Hieken T, Marler K, Patel M, Wild L, et al.
J Clin Oncol . 1998 Jul; 16(7):2409-16. PMID: 9667258
Purpose: To determine the significance of plasma c-erbB-2 levels to assess the extent of disease spread and to predict the response to chemotherapy in node-positive breast cancer patients. Methods: We...