R G Meeks
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Explore the profile of R G Meeks including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
90
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Recent Articles
1.
Cassidy S, Dotti A, Kolesar G, Dochterman L, Meeks R, Chevalier H
Int J Toxicol
. 2002 Jan;
20(6):391-9.
PMID: 11797821
Hexamethyldisiloxane (HMDS) is a volatile linear siloxane dimer used in many applications, including precision cleaning, active ingredient carrier, and as a manufacturing intermediate. The purpose of this study was to...
2.
McKim Jr J, Wilga P, Breslin W, Plotzke K, Gallavan R, Meeks R
Toxicol Sci
. 2001 Aug;
63(1):37-46.
PMID: 11509742
The cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) have numerous industrial and consumer applications and thus have the potential for human exposure. The present study was undertaken...
3.
McKim Jr J, Kolesar G, Jean P, Meeker L, Wilga P, Schoonhoven R, et al.
Toxicol Appl Pharmacol
. 2001 Apr;
172(2):83-92.
PMID: 11298494
Octamethylcyclotetrasiloxane (D4) has been described as a phenobarbital-like inducer of hepatic enzymes. Phenobarbital (PB) and phenobarbital-like chemicals induce transient hepatic and thyroid hyperplasia and sustained hypertrophy in rats and mice....
4.
Plotzke K, Crofoot S, Ferdinandi E, Beattie J, Reitz R, McNett D, et al.
Drug Metab Dispos
. 2000 Jan;
28(2):192-204.
PMID: 10640518
The retention, distribution, metabolism, and excretion of [(14)C]octamethylcyclotetrasiloxane (D(4)) were studied in Fischer 344 rats after single and multiple exposures to 7, 70, or 700 ppm [(14)C]D(4). Subset groups were...
5.
Meeks R
Environ Health Perspect
. 1999 Aug;
107(9):A440-1; author reply A444-5.
PMID: 10610316
No abstract available.
6.
McKim Jr J, Choudhuri S, Wilga P, Madan A, Burns-Naas L, Gallavan R, et al.
Toxicol Sci
. 1999 Aug;
50(1):10-9.
PMID: 10445748
Decamethylcyclopentasiloxane (D5) is a cyclic siloxane with a wide range of commercial applications. The present study was designed to investigate the effects of D5 on the expression and activity of...
7.
Burns-Naas L, Mast R, Meeks R, Mann P, Thevenaz P
Toxicol Sci
. 1998 Aug;
43(2):230-40.
PMID: 9710964
D5 is a low-molecular-weight cyclic siloxane used for industrial and consumer product applications. The objective of the present study was to evaluate the subchronic toxicity of D5 following a 3-month...
8.
McKim Jr J, Wilga P, Kolesar G, Choudhuri S, Madan A, Dochterman L, et al.
Toxicol Sci
. 1998 Apr;
41(1):29-41.
PMID: 9520339
Repeated inhalation exposure to octamethylcyclotetrasiloxane (D4) produces a reversible and dose-related hepatomegaly and proliferation of hepatic endoplasmic reticulum in rats. However, the effects of D4 on the expression of cytochrome...
9.
Kolesar G, Siddiqui W, Crofoot S, Evans M, Meeks R
Fundam Appl Toxicol
. 1995 Apr;
25(1):52-9.
PMID: 7601327
The purpose of this study was to evaluate the inhalation toxicity of 1,1,1,3-tetrachloropropane (TCP), an intermediate in the production of chlorinated silicone fluids. Male and female Sprague-Dawley rats were exposed...
10.
Siddiqui W, SCHARDEIN J, Cassidy S, Meeks R
Fundam Appl Toxicol
. 1994 Oct;
23(3):377-81.
PMID: 7835538
The purpose of these studies was to assess the potential adverse effects of silicone breast implant envelope elastomer on general reproduction and fetal development in rats and rabbits. One control...