R G J Westendorp
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Explore the profile of R G J Westendorp including associated specialties, affiliations and a list of published articles.
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106
Citations
2901
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Recent Articles
1.
Du Puy R, Postmus I, Stott D, Blum M, Poortvliet R, den Elzen W, et al.
BMC Endocr Disord
. 2018 Sep;
18(1):67.
PMID: 30231866
Background: Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of...
2.
Rozing M, Veerhuis R, Westendorp R, Eikelenboom P, Stek M, Marijnissen R, et al.
Psychoneuroendocrinology
. 2018 Sep;
99:20-27.
PMID: 30172071
Objective: Different biological mechanisms may underlie depression beginning in early life (early-onset) and depression beginning later in life (late-onset). Although the relation between inflammation and depression has been studied extensively,...
3.
Justice A, Winkler T, Feitosa M, Graff M, Fisher V, Young K, et al.
Nat Commun
. 2017 Apr;
8:14977.
PMID: 28443625
Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data...
4.
Waaijer M, Westendorp R, Goldeck D, Gunn D, Pawelec G, Stijntjes M, et al.
Exp Gerontol
. 2016 Apr;
87(Pt B):175-181.
PMID: 27045974
In addition to measures already used in clinical practice, molecular measures have been proposed to assess health status, but these have not yet been introduced into clinical practice. We aimed...
5.
Trompet S, Postmus I, Slagboom P, Heijmans B, Smit R, Maier A, et al.
Eur J Clin Pharmacol
. 2015 Dec;
72(4):431-7.
PMID: 26686871
Purpose: In pharmacogenetic research, genetic variation in non-responders and high responders is compared with the aim to identify the genetic loci responsible for this variation in response. However, an important...
6.
Jansen S, Akintola A, Roelfsema F, van der Spoel E, M Cobbaert C, Ballieux B, et al.
Sci Rep
. 2015 Jun;
5:11525.
PMID: 26089239
Few studies have included subjects with the propensity to reach old age in good health, with the aim to disentangle mechanisms contributing to staying healthier for longer. The hypothalamic-pituitary-thyroid (HPT)...
7.
Lindenberg J, Westendorp R
J Soc Work Pract
. 2015 Jun;
29(1):85-98.
PMID: 26028795
In this article, we explore views on an age-friendly space in the Netherlands by analysing the responses of older individuals ( = 54) in focus groups and by examining the...
8.
Gunn D, Dick J, Van Heemst D, Griffiths C, Tomlin C, Murray P, et al.
Br J Dermatol
. 2015 Jan;
172(5):1338-45.
PMID: 25627783
Background: Lifestyle has been proven to have a dramatic effect on the risk of age-related diseases. The association of lifestyle and facial ageing has been less well studied. Objectives: To...
9.
van Vliet P, Sabayan B, Wijsman L, Poortvliet R, Mooijaart S, de Ruijter W, et al.
Neurology
. 2014 Aug;
83(13):1192-9.
PMID: 25142900
Objective: To study the relation between N-terminal pro-brain natriuretic peptide (NT-proBNP) levels, used as a marker of heart failure in clinical practice, blood pressure (BP), and cognitive decline in the...
10.
van Exel E, Eikelenboom P, Comijs H, Deeg D, Stek M, Westendorp R
Neurobiol Aging
. 2013 Sep;
35(3):725.e7-10.
PMID: 24054991
Insulin-like growth factor-1 (IGF-1), part of an evolutionary conserved signaling pathway in both mammalian and non-mammalian species, is inferred in neurodegenerative disorders including Alzheimer's disease (AD). A murine model for...