R E Hancock
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Explore the profile of R E Hancock including associated specialties, affiliations and a list of published articles.
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Articles
239
Citations
12531
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Recent Articles
1.
Hancock R, Exner M
Methods Mol Med
. 2011 Feb;
8:191-204.
PMID: 21351034
The outer membranes of Gram-negative bacteria represent selective, permeability barriers to environmental molecules. This function is accomplished in two ways. First, outer membranes exclude many larger hydrophilic molecules, including enzymes...
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3.
Hancock R
Expert Opin Investig Drugs
. 2005 Jul;
7(2):167-74.
PMID: 15991950
Novel classes of antibiotics that are useful against resistant bacteria are a major need in human medicine. Cationic antimicrobial peptides are utilised as nature's antibiotics, being produced constitutively or in...
4.
Gatto N, Dabo S, Hancock R, Confer A
Vet Microbiol
. 2002 Jun;
87(3):221-35.
PMID: 12052333
Pasteurella multocida A:3 is a major cause of bovine pneumonia. A major antigenic heat-modifiable 28kDa outer membrane protein (Omp28) was previously identified. The purpose of this study was to purify...
5.
Hancock R
Lancet Infect Dis
. 2002 Mar;
1(3):156-64.
PMID: 11871492
Cationic antimicrobial peptides are produced by all organisms, from plants and insects to human beings, as a major part of their immediately effective, non-specific defences against infections. With the increasing...
6.
Lange C, Hancock R, Samuel J, Finlay W
J Pharm Sci
. 2001 Dec;
90(10):1647-57.
PMID: 11745723
A liposome encapsulation was optimized for the entrapment and aerosol delivery of an alpha-helical cationic peptide, CM3, which had shown good antimicrobial and antiendotoxin activity in vitro. The encapsulation procedure...
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8.
Zhang L, Rozek A, Hancock R
J Biol Chem
. 2001 Jul;
276(38):35714-22.
PMID: 11473117
A series of natural and synthetic cationic antimicrobial peptides from various structural classes, including alpha-helical, beta-sheet, extended, and cyclic, were examined for their ability to interact with model membranes, assessing...
9.
Luchette P, Vetman T, Prosser R, Hancock R, Nieh M, Glinka C, et al.
Biochim Biophys Acta
. 2001 Jul;
1513(2):83-94.
PMID: 11470082
Bilayered micelles, or bicelles, which consist of a mixture of long- and short-chain phospholipids, are a popular model membrane system. Depending on composition, concentration, and temperature, bicelle mixtures may adopt...
10.
Brinkman F, Macfarlane E, Warrener P, Hancock R
Infect Immun
. 2001 Jul;
69(8):5207-11.
PMID: 11447209
A strong relationship between virulence-associated sensor histidine kinases of fungi and those in Streptomyces coelicolor was observed, and phylogenetic analysis suggested that bacterium-to-eukaryote horizontal gene transfer had occurred between ancestors...