R de Waal Malefyt
Overview
Explore the profile of R de Waal Malefyt including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ayanoglu G, Desai B, Fick Jr R, Grein J, de Waal Malefyt R, Mattson J, et al.
Eur Respir J
. 2010 Jul;
37(3):541-52.
PMID: 20650997
The aim of the present study was to determine whether systemic sensitisation and chronic aeroallergen challenge in macaques replicate the classical and emerging immunology and molecular pathology of human asthma....
2.
Corrigan C, Jayaratnam A, Wang Y, Liu Y, de Waal Malefyt R, Meng Q, et al.
Allergy
. 2009 Feb;
64(7):1014-22.
PMID: 19187393
Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor...
3.
CREPALDI L, Gasperini S, Lapinet J, Calzetti F, Pinardi C, Liu Y, et al.
J Immunol
. 2001 Aug;
167(4):2312-22.
PMID: 11490020
We have recently shown that IL-10 fails to trigger Stat3 and Stat1 tyrosine phosphorylation in freshly isolated human neutrophils. In this study, we report that IL-10 can nonetheless induce Stat3...
4.
van der Velden V, Laan M, Baert M, de Waal Malefyt R, Neijens H, Savelkoul H
Clin Exp Allergy
. 2001 Jul;
31(7):997-1006.
PMID: 11467989
Background: The immunological processes in early life and their relation to allergic sensitization leading to a Th2 cytokine profile are still not well understood. Objective: To analyse the environmental and...
5.
Reche P, Soumelis V, Gorman D, Clifford T, Liu Mr , Travis M, et al.
J Immunol
. 2001 Jun;
167(1):336-43.
PMID: 11418668
The sequence of a novel hemopoietic cytokine was discovered in a computational screen of genomic databases, and its homology to mouse thymic stromal lymphopoietin (TSLP) suggests that it is the...
6.
Levings M, Sangregorio R, Galbiati F, Squadrone S, de Waal Malefyt R, Roncarolo M
J Immunol
. 2001 Apr;
166(9):5530-9.
PMID: 11313392
CD4(+) T regulatory type 1 (Tr1) cells suppress Ag-specific immune responses in vitro and in vivo. Although IL-10 is critical for the differentiation of Tr1 cells, the effects of other...
7.
Moore K, de Waal Malefyt R, Coffman R, OGarra A
Annu Rev Immunol
. 2001 Mar;
19:683-765.
PMID: 11244051
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell...
8.
Debets R, Timans J, Churakowa T, Zurawski S, de Waal Malefyt R, Moore K, et al.
J Immunol
. 2000 Oct;
165(9):4950-6.
PMID: 11046021
IL-18 is critical in eliciting IFN-gamma production from Th1 cells both in vitro and in vivo. Th1 cells have been implicated in the pathogenesis of autoimmune disorders, making antagonists of...
9.
De Rossi M, Bernasconi P, Baggi F, de Waal Malefyt R, Mantegazza R
Int Immunol
. 2000 Sep;
12(9):1329-35.
PMID: 10967028
The idiopathic inflammatory myopathies are characterized by antibody- or cell-mediated immune response against unknown muscle tissue antigens. In these diseases a cellular infiltrate, composed of T and B lymphocytes, macrophages...
10.
Lund-Johansen F, Davis K, Bishop J, de Waal Malefyt R
Cytometry
. 2000 Mar;
39(4):250-9.
PMID: 10738277
Background: Activation-induced protein phosphorylation can be studied by Western blotting, but this method is time consuming and depends on the use of radioactive probes for quantitation. We present a novel...