R Daniel Kortschak
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Explore the profile of R Daniel Kortschak including associated specialties, affiliations and a list of published articles.
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26
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789
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Recent Articles
1.
Gemmell N, Rutherford K, Prost S, Tollis M, Winter D, Macey J, et al.
Nature
. 2020 Aug;
585(7823):E3.
PMID: 32811988
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Gemmell N, Rutherford K, Prost S, Tollis M, Winter D, Macey J, et al.
Nature
. 2020 Aug;
584(7821):403-409.
PMID: 32760000
The tuatara (Sphenodon punctatus)-the only living member of the reptilian order Rhynchocephalia (Sphenodontia), once widespread across Gondwana-is an iconic species that is endemic to New Zealand. A key link to...
3.
Cui J, Qu Z, Harata-Lee Y, Shen H, Aung T, Wang W, et al.
PLoS One
. 2020 Jul;
15(7):e0236395.
PMID: 32730293
Traditional Chinese Medicine (TCM) preparations are often extracts of single or multiple herbs containing hundreds of compounds, and hence it has been difficult to study their mechanisms of action. Compound...
4.
Shen H, Qu Z, Harata-Lee Y, Cui J, Aung T, Wang W, et al.
Sci Rep
. 2019 Nov;
9(1):15889.
PMID: 31685921
Drug-drug interactions (DDIs), especially with herbal medicines, are complex, making it difficult to identify potential molecular mechanisms and targets. We introduce a workflow to carry out DDI research using transcriptome...
5.
Shen H, Qu Z, Harata-Lee Y, Aung T, Cui J, Wang W, et al.
Front Oncol
. 2019 Aug;
9:632.
PMID: 31380274
Herbal compatibility is the knowledge of which herbs to combine in traditional Chinese medicine (TCM) formulations. The lack of understanding of herbal compatibility is one of the key problems for...
6.
Ivancevic A, Kortschak R, Bertozzi T, Adelson D
Genome Biol
. 2018 Jul;
19(1):85.
PMID: 29983116
Background: Transposable elements (TEs) are mobile DNA sequences, colloquially known as jumping genes because of their ability to replicate to new genomic locations. TEs can jump between organisms or species...
7.
Zeng L, Pederson S, Kortschak R, Adelson D
Mob DNA
. 2018 Jun;
9:17.
PMID: 29942365
Background: Transposable elements (TEs) are primarily responsible for the DNA losses and gains in genome sequences that occur over time within and between species. TEs themselves evolve, with clade specific...
8.
Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse
Buckley R, Kortschak R, Adelson D
PLoS Comput Biol
. 2018 Apr;
14(4):e1006091.
PMID: 29677183
The forces driving the accumulation and removal of non-coding DNA and ultimately the evolution of genome size in complex organisms are intimately linked to genome structure and organisation. Our analysis...
9.
Zeng L, Kortschak R, Raison J, Bertozzi T, Adelson D
PLoS One
. 2018 Mar;
13(3):e0193588.
PMID: 29538441
Transposable Elements (TEs) are mobile DNA sequences that make up significant fractions of amniote genomes. However, they are difficult to detect and annotate ab initio because of their variable features,...
10.
Palkopoulou E, Lipson M, Mallick S, Nielsen S, Rohland N, Baleka S, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(11):E2566-E2574.
PMID: 29483247
Elephantids are the world's most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a total of 14 genomes, including 2 from the American...