R D Hannan
Overview
Explore the profile of R D Hannan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
703
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Gilan O, Diesch J, Amalia M, Jastrzebski K, Chueh A, Verrills N, et al.
Oncogene
. 2015 Mar;
34(10):1340.
PMID: 25740609
No abstract available.
2.
Gilan O, Diesch J, Amalia M, Jastrzebski K, Chueh A, Verrills N, et al.
Oncogene
. 2014 Mar;
34(10):1333-9.
PMID: 24632621
The proto-oncogene c-Jun is a component of activator protein-1 (AP-1) transcription factor complexes that regulates processes essential for embryonic development, tissue homeostasis and malignant transformation. Induction of gene expression by...
3.
Poortinga G, Quinn L, Hannan R
Oncogene
. 2014 Mar;
34(4):403-12.
PMID: 24608428
The MYC oncoprotein and transcription factor is dysregulated in a majority of human cancers and is considered a major driver of the malignant phenotype. As such, developing drugs for effective...
4.
Hannan K, Sanij E, Rothblum L, Hannan R, Pearson R
Biochim Biophys Acta
. 2012 Nov;
1829(3-4):342-60.
PMID: 23153826
Transcription of the ribosomal RNA genes by the dedicated RNA polymerase I enzyme and subsequent processing of the ribosomal RNA are fundamental control steps in the synthesis of functional ribosomes....
5.
Astle M, Hannan K, Ng P, Lee R, George A, Hsu A, et al.
Oncogene
. 2011 Sep;
31(15):1949-62.
PMID: 21909130
The phosphatidylinositol 3-kinase (PI3K)/AKT and RAS oncogenic signalling modules are frequently mutated in sporadic human cancer. Although each of these pathways has been shown to play critical roles in driving...
6.
Pakay J, Diesch J, Gilan O, Yip Y, Sayan E, Kolch W, et al.
Oncogene
. 2011 Aug;
31(14):1817-24.
PMID: 21874050
Fos-related antigen-1 (Fra-1) is a member of the Activator Protein-1 (AP-1) transcription factor superfamily that is overexpressed in a variety of cancers, including colon, breast, lung, bladder and brain. High...
7.
Bathgate R, Lekgabe E, McGuane J, Su Y, Pham T, Ferraro T, et al.
Mol Cell Endocrinol
. 2007 Oct;
280(1-2):30-8.
PMID: 17961912
We have evaluated the effectiveness of systemic adenovirally delivered mouse relaxin on reversing fibrosis in a transgenic murine model of fibrotic cardiomyopathy due to beta(2)-adrenergic receptor (beta(2)AR) overexpression. Recombinant adenoviruses...
8.
Smith N, Chan H, Osborne J, Thomas W, Hannan R
Cell Mol Life Sci
. 2004 Nov;
61(21):2695-703.
PMID: 15549170
Activation of the type 1 angiotensin II receptor (AT(1)R) is associated with the aetiology of left ventricular hypertrophy, although the exact intracellular signalling mechanism(s) remain unclear. Transactivation of the epidermal...
9.
Hannan R, Jenkins A, Jenkins A, Brandenburger Y
Clin Exp Pharmacol Physiol
. 2003 Aug;
30(8):517-27.
PMID: 12890171
1. Left ventricular hypertrophy (LVH) of the heart is an adaptive response to sustained increases in blood pressure and hormone imbalances. Left ventricular hypertrophy is associated with programmed responses at...
10.
Brandenburger Y, Jenkins A, Autelitano D, Hannan R
FASEB J
. 2001 Aug;
15(11):2051-3.
PMID: 11511532
Recent evidence suggests that increased translational efficiency of existing ribosomes alone is insufficient to account for the hypertrophic growth of cardiomyocytes and that synthesis of new functional ribosomes must occur....