R D Fleischmann
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Explore the profile of R D Fleischmann including associated specialties, affiliations and a list of published articles.
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33
Citations
8581
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Recent Articles
11.
Jhappan C, Morse 3rd H, Fleischmann R, Gottesman M, Merlino G
Nat Genet
. 1997 Dec;
17(4):483-6.
PMID: 9398856
Severe combined immunodeficiency (SCID) mice are defective in their ability to rearrange their variable (V), diversity (D) and joining (J) genetic elements to generate functional immunoglobulin (Ig) and T-cell receptor...
12.
Klenk H, Clayton R, Tomb J, White O, Nelson K, Ketchum K, et al.
Nature
. 1997 Dec;
390(6658):364-70.
PMID: 9389475
Archaeoglobus fulgidus is the first sulphur-metabolizing organism to have its genome sequence determined. Its genome of 2,178,400 base pairs contains 2,436 open reading frames (ORFs). The information processing systems and...
13.
Tomb J, White O, Kerlavage A, Clayton R, Sutton G, Fleischmann R, et al.
Nature
. 1997 Aug;
388(6642):539-47.
PMID: 9252185
Helicobacter pylori, strain 26695, has a circular genome of 1,667,867 base pairs and 1,590 predicted coding sequences. Sequence analysis indicates that H. pylori has well-developed systems for motility, for scavenging...
14.
Fraser C, Fleischmann R
Electrophoresis
. 1997 Aug;
18(8):1207-16.
PMID: 9298642
The introduction of methods for automated DNA sequence analysis nearly a decade ago, together with more recent advances in the field of bioinformatics, have revolutionized biology and medicine and have...
15.
Hood D, Deadman M, Jennings M, Bisercic M, Fleischmann R, Venter J, et al.
Proc Natl Acad Sci U S A
. 1996 Oct;
93(20):11121-5.
PMID: 8855319
The whole genome sequence (1.83 Mbp) of Haemophilus influenzae strain Rd was searched to identify tandem oligonucleotide repeat sequences. Loss or gain of one or more nucleotide repeats through a...
16.
Bult C, White O, Olsen G, Zhou L, Fleischmann R, Sutton G, et al.
Science
. 1996 Aug;
273(5278):1058-73.
PMID: 8688087
The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of...
17.
Fraser C, Gocayne J, White O, Adams M, Clayton R, Fleischmann R, et al.
Science
. 1995 Oct;
270(5235):397-403.
PMID: 7569993
The complete nucleotide sequence (580,070 base pairs) of the Mycoplasma genitalium genome, the smallest known genome of any free-living organism, has been determined by whole-genome random sequencing and assembly. A...
18.
Adams M, Kerlavage A, Fleischmann R, Fuldner R, Bult C, Lee N, et al.
Nature
. 1995 Sep;
377(6547 Suppl):3-174.
PMID: 7566098
In an effort to identify new genes and analyse their expression patterns, 174,472 partial complementary DNA sequences (expressed sequence tags (ESTs)), totalling more than 52 million nucleotides of human DNA...
19.
Smith H, Tomb J, Dougherty B, Fleischmann R, Venter J
Science
. 1995 Jul;
269(5223):538-40.
PMID: 7542802
The naturally transformable, Gram-negative bacterium Haemophilus influenzae Rd preferentially takes up DNA of its own species by recognizing a 9-base pair sequence, 5'-AAGTGCGGT, carried in multiple copies in its chromosome....
20.
Fleischmann R, Adams M, White O, Clayton R, Kirkness E, Kerlavage A, et al.
Science
. 1995 Jul;
269(5223):496-512.
PMID: 7542800
An approach for genome analysis based on sequencing and assembly of unselected pieces of DNA from the whole chromosome has been applied to obtain the complete nucleotide sequence (1,830,137 base...