R D Fleischmann
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Explore the profile of R D Fleischmann including associated specialties, affiliations and a list of published articles.
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33
Citations
8581
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Recent Articles
1.
Fleischmann R, Alland D, Eisen J, Carpenter L, White O, Peterson J, et al.
J Bacteriol
. 2002 Sep;
184(19):5479-90.
PMID: 12218036
Virulence and immunity are poorly understood in Mycobacterium tuberculosis. We sequenced the complete genome of the M. tuberculosis clinical strain CDC1551 and performed a whole-genome comparison with the laboratory strain...
2.
Fraser C, Eisen J, Fleischmann R, Ketchum K, Peterson S
Emerg Infect Dis
. 2000 Sep;
6(5):505-12.
PMID: 10998382
The sequences of close to 30 microbial genomes have been completed during the past 5 years, and the sequences of more than 100 genomes should be completed in the next...
3.
Califano J, Kitten T, Lewis J, Macrina F, Fleischmann R, Fraser C, et al.
Infect Immun
. 2000 Aug;
68(9):5247-53.
PMID: 10948151
Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions, and its presence in subgingival plaque significantly increases the risk for periodontitis. In contrast to many bacterial pathogens, P....
4.
Nierman W, Eisen J, Fleischmann R, Fraser C
Curr Opin Struct Biol
. 2000 Jun;
10(3):343-8.
PMID: 10851186
Genome sequence information has continued to accumulate at a spectacular pace during the past year. Details of the sequence and gene content of human chromosome 22 were published. The sequencing...
5.
Tettelin H, Saunders N, Heidelberg J, Jeffries A, Nelson K, Eisen J, et al.
Science
. 2000 Mar;
287(5459):1809-15.
PMID: 10710307
The 2,272,351-base pair genome of Neisseria meningitidis strain MC58 (serogroup B), a causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (53.7%) of which were assigned a...
6.
White O, Eisen J, Heidelberg J, Hickey E, Peterson J, Dodson R, et al.
Science
. 1999 Nov;
286(5444):1571-7.
PMID: 10567266
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid...
7.
Dong H, Chen T, Dewhirst F, Fleischmann R, Fraser C, Duncan M
Infect Immun
. 1999 Jun;
67(7):3416-23.
PMID: 10377121
The Porphyromonas gingivalis genome contains multiple copies of insertion element IS1126. When chromosomal DNA digests of different strains were probed with IS1126, between 25 and 35 hybridizing fragments per genome...
8.
Nelson K, Clayton R, Gill S, Gwinn M, Dodson R, Haft D, et al.
Nature
. 1999 Jun;
399(6734):323-9.
PMID: 10360571
The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis...
9.
Delcher A, Kasif S, Fleischmann R, Peterson J, White O, Salzberg S
Nucleic Acids Res
. 1999 May;
27(11):2369-76.
PMID: 10325427
A new system for aligning whole genome sequences is described. Using an efficient data structure called a suffix tree, the system is able to rapidly align sequences containing millions of...
10.
Fraser C, Casjens S, Huang W, Sutton G, Clayton R, Lathigra R, et al.
Nature
. 1997 Dec;
390(6660):580-6.
PMID: 9403685
The genome of the bacterium Borrelia burgdorferi B31, the aetiologic agent of Lyme disease, contains a linear chromosome of 910,725 base pairs and at least 17 linear and circular plasmids...